Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

Multivalent proteins undergo coupled segregative and associative phase transitions. Phase separation, a segregative transition, is driven by macromolecular solubility, and this leads to coexisting phases above system-specific saturation concentrations. Percolation is a continuous transition that is...

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Detalles Bibliográficos
Autores principales: Kar, Mrityunjoy, Vogel, Laura T., Chauhan, Gaurav, Ausserwöger, Hannes, Welsh, Timothy J., Kamath, Anjana R., Knowles, Tuomas P. J., Hyman, Anthony A., Seidel, Claus A. M., Pappu, Rohit V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543311/
https://www.ncbi.nlm.nih.gov/pubmed/37790538
http://dx.doi.org/10.21203/rs.3.rs-3252197/v1

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