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CD73 mediates the therapeutic effects of endometrial regenerative cells in concanavalin A-induced hepatitis by regulating CD4(+) T cells

BACKGROUND: As a kind of mesenchymal-like stromal cells, endometrial regenerative cells (ERCs) have been demonstrated effective in the treatment of Concanavalin A (Con A)-induced hepatitis. However, the therapeutic mechanism of ERCs is not fully understood. Ecto-5`-nucleotidase (CD73), an enzyme tha...

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Detalles Bibliográficos
Autores principales: Qin, Hong, Sun, Chenglu, Kong, Dejun, Zhu, Yanglin, Shao, Bo, Ren, Shaohua, Wang, Hongda, Zhang, Jingyi, Xu, Yini, Wang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543328/
https://www.ncbi.nlm.nih.gov/pubmed/37775797
http://dx.doi.org/10.1186/s13287-023-03505-2