Case series of intestinal microsporidiosis in non-HIV patients caused by Encephalitozoon hellem

Intestinal microsporidiosis is most often caused by Enterocytozoon bieneusi, and to a lesser extent by species of the genus Encephalitozoon. Until now, Encephalitozoon hellem was not clearly known to induce disease restricted to the intestine, or rarely in HIV subjects or in tropical countries. We r...

Descripción completa

Detalles Bibliográficos
Autores principales: Nourrisson, Céline, Hamane, Samia, Bonhomme, Julie, Durieux, Marie-Fleur, Foulquier, Jean-Baptiste, Lesthelle, Sophie, Moniot, Maxime, French microsporidiosis network, Bougnoux, Marie-Elisabeth, Poirier, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543343/
https://www.ncbi.nlm.nih.gov/pubmed/37706342
http://dx.doi.org/10.1080/22221751.2023.2258997
Descripción
Sumario:Intestinal microsporidiosis is most often caused by Enterocytozoon bieneusi, and to a lesser extent by species of the genus Encephalitozoon. Until now, Encephalitozoon hellem was not clearly known to induce disease restricted to the intestine, or rarely in HIV subjects or in tropical countries. We report here 11 cases of delineated intestinal microsporidioses due to E. hellem diagnosed in France in non-HIV patients. Briefly, all patients were immunocompromised. They all suffered from diarrhoea, associated in nearly 50% of cases with weight loss. Concerning treatment, 5/11 patients had a discontinuation or a decrease of their immunosuppressive therapy, and 4/11 received albendazole. All patients recovered. Five different genotypes were identified based on the rRNA ITS sequence.

Ejemplares similares