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Mechanical loading-induced change of bone homeostasis is mediated by PGE2-driven hypothalamic interoception
Bone is a mechanosensitive tissue and undergoes constant remodeling to adapt to the mechanical loading environment. However, it is unclear whether the signals of bone cells in response to mechanical stress are processed and interpreted in the brain. In this study, we found that the hypothalamus of t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Journal Experts
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543368/ https://www.ncbi.nlm.nih.gov/pubmed/37790467 http://dx.doi.org/10.21203/rs.3.rs-3325498/v1 |