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MIM-CyCIF: Masked Imaging Modeling for Enhancing Cyclic Immunofluorescence (CyCIF) with Panel Reduction and Imputation

CyCIF can quantify multiple biomarkers, but panel capacity is limited by technical challenges. We propose a computational panel reduction approach that can impute the information content from 25 markers using only 9 markers, learning co-expression and morphological patterns while concurrently increa...

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Detalles Bibliográficos
Autores principales: Chang, Young Hwan, Sims, Zachary, Mills, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543389/
https://www.ncbi.nlm.nih.gov/pubmed/37790506
http://dx.doi.org/10.21203/rs.3.rs-3270272/v1