Increased AID Results in Mutations at the CRLF2 Locus Implicated in Latin American ALL Health Disparities

Activation-induced cytidine deaminase (AID) is a B cell-specific base editor required during class switch recombination and somatic hypermutation for B cell maturation and antibody diversification. However, it has also been implicated as a factor in the etiology of several B cell malignancies. Evalu...

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Detalles Bibliográficos
Autores principales: Pannunzio, Nicholas, Rangel, Valeria, Sterrenberg, Jason, Garawi, Aya, Mezcord, Vyanka, Folkerts, Melissa, Caulderon, Sabrina, Wang, Jinglong, Soyfer, Eli, Eng, Oliver, Valerin, Jennifer, Tanjasiri, Sora, Quintero-Rivera, Fabiola, Masri, Selma, Seldin, Marcus, Frock, Richard, Fleischman, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543404/
https://www.ncbi.nlm.nih.gov/pubmed/37790327
http://dx.doi.org/10.21203/rs.3.rs-3332673/v1

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