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The RhoA GTPase regulates Type I Interferon Signaling in Systemic lupus erythematosus

OBJECTIVE. Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by abnormal activation of the type I interferon (IFN) pathway, which results in tissue inflammation and organ damage. We explored the role of the RhoA GTPase in the type I IFN activation pathway to provide a potent...

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Detalles Bibliográficos
Autores principales: Fan, Wei, Wei, Bo, Chen, Xuyan, Zhang, Yi, Xiao, Pingping, Li, Kaiyan, Zhang, Yi qin, Huang, Jinmei, Leng, Lin, Bucala, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543431/
https://www.ncbi.nlm.nih.gov/pubmed/37790522
http://dx.doi.org/10.21203/rs.3.rs-3320841/v1