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Structural insights into dimerization and activation of the mGlu2–mGlu3 and mGlu2–mGlu4 heterodimers
Heterodimerization of the metabotropic glutamate receptors (mGlus) has shown importance in the functional modulation of the receptors and offers potential drug targets for treating central nervous system diseases. However, due to a lack of molecular details of the mGlu heterodimers, understanding of...
Autores principales: | Wang, Xinwei, Wang, Mu, Xu, Tuo, Feng, Ye, Shao, Qiang, Han, Shuo, Chu, Xiaojing, Xu, Yechun, Lin, Shuling, Zhao, Qiang, Wu, Beili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543438/ https://www.ncbi.nlm.nih.gov/pubmed/37286794 http://dx.doi.org/10.1038/s41422-023-00830-2 |
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