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Structural insights into dimerization and activation of the mGlu2–mGlu3 and mGlu2–mGlu4 heterodimers

Heterodimerization of the metabotropic glutamate receptors (mGlus) has shown importance in the functional modulation of the receptors and offers potential drug targets for treating central nervous system diseases. However, due to a lack of molecular details of the mGlu heterodimers, understanding of...

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Detalles Bibliográficos
Autores principales: Wang, Xinwei, Wang, Mu, Xu, Tuo, Feng, Ye, Shao, Qiang, Han, Shuo, Chu, Xiaojing, Xu, Yechun, Lin, Shuling, Zhao, Qiang, Wu, Beili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543438/
https://www.ncbi.nlm.nih.gov/pubmed/37286794
http://dx.doi.org/10.1038/s41422-023-00830-2

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