Advances in the regulation of adipogenesis and lipid metabolism by exosomal ncRNAs and their role in related metabolic diseases

Exosomes are membrane-bound extracellular vesicles released following the fusion of multivesicular bodies (MVBs) with the cell membrane. Exosomes transport diverse molecules, including proteins, lipids, DNA and RNA, and regulate distant intercellular communication. Noncoding RNA (ncRNAs) carried by...

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Detalles Bibliográficos
Autores principales: Liu, Cong, Liu, Xilin, Li, Hong, Kang, Zhichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543472/
https://www.ncbi.nlm.nih.gov/pubmed/37791070
http://dx.doi.org/10.3389/fcell.2023.1173904
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author Liu, Cong
Liu, Xilin
Li, Hong
Kang, Zhichen
author_facet Liu, Cong
Liu, Xilin
Li, Hong
Kang, Zhichen
author_sort Liu, Cong
collection PubMed
description Exosomes are membrane-bound extracellular vesicles released following the fusion of multivesicular bodies (MVBs) with the cell membrane. Exosomes transport diverse molecules, including proteins, lipids, DNA and RNA, and regulate distant intercellular communication. Noncoding RNA (ncRNAs) carried by exosomes regulate cell-cell communication in tissues, including adipose tissue. This review summarizes the action mechanisms of ncRNAs carried by exosomes on adipocyte differentiation and modulation of adipogenesis by exosomal ncRNAs. This study aims to provide valuable insights for developing novel therapeutics.
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spelling pubmed-105434722023-10-03 Advances in the regulation of adipogenesis and lipid metabolism by exosomal ncRNAs and their role in related metabolic diseases Liu, Cong Liu, Xilin Li, Hong Kang, Zhichen Front Cell Dev Biol Cell and Developmental Biology Exosomes are membrane-bound extracellular vesicles released following the fusion of multivesicular bodies (MVBs) with the cell membrane. Exosomes transport diverse molecules, including proteins, lipids, DNA and RNA, and regulate distant intercellular communication. Noncoding RNA (ncRNAs) carried by exosomes regulate cell-cell communication in tissues, including adipose tissue. This review summarizes the action mechanisms of ncRNAs carried by exosomes on adipocyte differentiation and modulation of adipogenesis by exosomal ncRNAs. This study aims to provide valuable insights for developing novel therapeutics. Frontiers Media S.A. 2023-09-18 /pmc/articles/PMC10543472/ /pubmed/37791070 http://dx.doi.org/10.3389/fcell.2023.1173904 Text en Copyright © 2023 Liu, Liu, Li and Kang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Liu, Cong
Liu, Xilin
Li, Hong
Kang, Zhichen
Advances in the regulation of adipogenesis and lipid metabolism by exosomal ncRNAs and their role in related metabolic diseases
title Advances in the regulation of adipogenesis and lipid metabolism by exosomal ncRNAs and their role in related metabolic diseases
title_full Advances in the regulation of adipogenesis and lipid metabolism by exosomal ncRNAs and their role in related metabolic diseases
title_fullStr Advances in the regulation of adipogenesis and lipid metabolism by exosomal ncRNAs and their role in related metabolic diseases
title_full_unstemmed Advances in the regulation of adipogenesis and lipid metabolism by exosomal ncRNAs and their role in related metabolic diseases
title_short Advances in the regulation of adipogenesis and lipid metabolism by exosomal ncRNAs and their role in related metabolic diseases
title_sort advances in the regulation of adipogenesis and lipid metabolism by exosomal ncrnas and their role in related metabolic diseases
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543472/
https://www.ncbi.nlm.nih.gov/pubmed/37791070
http://dx.doi.org/10.3389/fcell.2023.1173904
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AT lihong advancesintheregulationofadipogenesisandlipidmetabolismbyexosomalncrnasandtheirroleinrelatedmetabolicdiseases
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