miR-146a-3p as a potential novel therapeutic by targeting MBD2 to mediate Th17 differentiation in Th17 predominant neutrophilic severe asthma

Th17 (T-helper 17) cells subtype of non-T2 (non-type 2) asthma is related to neutrophilic infiltration and resistance to inhaled corticosteroids (ICS), so is also known as severe asthma. Methyl-CpG binding domain protein 2 (MBD2) regulates the differentiation of the Th17 cells, tending to show a the...

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Detalles Bibliográficos
Autores principales: Duan, Wentao, Huang, Jin, Wasti, Binaya, Chen, Zhifeng, Yuan, Yu, He, Yi, Li, Danhong, Jia, Jingsi, Liu, Shaokun, Liu, Yi, Ma, Libing, Zeng, Qingping, zhu, Liming, Li, Jianmin, Zhang, Xiufeng, Xiang, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543568/
https://www.ncbi.nlm.nih.gov/pubmed/36961677
http://dx.doi.org/10.1007/s10238-023-01033-0

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