Cargando…

Bariatric surgery improves postprandial VLDL kinetics and restores insulin-mediated regulation of hepatic VLDL production

Dyslipidemia in obesity results from excessive production and impaired clearance of triglyceride-rich (TG-rich) lipoproteins, which are particularly pronounced in the postprandial state. Here, we investigated the impact of Roux-en-Y gastric bypass (RYGB) surgery on postprandial VLDL(1) and VLDL(2) a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yildirim, Vehpi, ter Horst, Kasper W., Gilijamse, Pim W., van Harskamp, Dewi, Schierbeek, Henk, Jansen, Hans, Schimmel, Alinda W.M., Nieuwdorp, Max, Groen, Albert K., Serlie, Mireille J., van Riel, Natal A.W., Dallinga-Thie, Geesje M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543721/ https://www.ncbi.nlm.nih.gov/pubmed/37432744 http://dx.doi.org/10.1172/jci.insight.166905

Ejemplares similares

The effect of dapagliflozin on apolipoprotein B and glucose fluxes in patients with type 2 diabetes and well‐controlled plasma LDL cholesterol
por: Bouter, Kristien E. C., et al.
Publicado: (2020)

VLDL-associated mutagenic activity.
por: Gomes, M. I., et al.
Publicado: (1982)

Postprandial Peaking and Plateauing of Triglycerides and VLDL in Patients with Underlying Cardiovascular Diseases Despite Treatment
por: Samson, Clarissa E., et al.
Publicado: (2012)

Triglyceride Rich Lipoprotein -LPL-VLDL Receptor and Lp(a)-VLDL Receptor Pathways for Macrophage Foam Cell Formation
por: Takahashi, Sadao
Publicado: (2017)

Postprandial apoE Isoform and Conformational Changes Associated with VLDL Lipolysis Products Modulate Monocyte Inflammation
por: den Hartigh, Laura J., et al.
Publicado: (2012)

Decreased GPIHBP1 protein levels in visceral adipose tissue partly underlie the hypertriglyceridemic phenotype in insulin resistance
por: Surendran, R. Preethi, et al.
Publicado: (2018)

Adiponectin Reduces Plasma Triglyceride by Increasing VLDL Triglyceride Catabolism
por: Qiao, Liping, et al.
Publicado: (2008)

In Vivo Inflammation Does Not Impair ABCA1-Mediated Cholesterol Efflux Capacity of HDL
por: Franssen, Remco, et al.
Publicado: (2012)

Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis
por: Whitacre, Brynne E., et al.
Publicado: (2021)

The Role of Heparan Sulfate and Neuropilin 2 in VEGFA Signaling in Human Endothelial Tip Cells and Non-Tip Cells during Angiogenesis In Vitro
por: Dallinga, Marchien G., et al.
Publicado: (2021)

Effects of Electronegative VLDL on Endothelium Damage in Metabolic Syndrome
por: Chen, Chu-Huang, et al.
Publicado: (2012)

VLDL receptor gene therapy for reducing atherogenic lipoproteins
por: Krauss, Ronald M., et al.
Publicado: (2023)

Decreases in the Serum VLDL-TG/Non-VLDL-TG Ratio from Early Stages of Chronic Hepatitis C: Alterations in TG-Rich Lipoprotein Levels
por: Nishimura, Motoi, et al.
Publicado: (2011)

ANGPTL3 Inhibition With Evinacumab Results in Faster Clearance of IDL and LDL apoB in Patients With Homozygous Familial Hypercholesterolemia—Brief Report
por: Reeskamp, Laurens F., et al.
Publicado: (2021)

Mathematical modelling of competitive LDL/VLDL binding and uptake by hepatocytes
por: Pearson, T., et al.
Publicado: (2008)

Progesterone Regulation of Milk Fat Globule Size Is VLDL Dependent
por: Argov-Argaman, Nurit, et al.
Publicado: (2020)

VLDL Hydrolysis by Hepatic Lipase Regulates PPARδ Transcriptional Responses
por: Brown, Jonathan D., et al.
Publicado: (2011)

ChREBP Rather Than SHP Regulates Hepatic VLDL Secretion
por: Niwa, Hiroyuki, et al.
Publicado: (2018)

Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice
por: Radović, Branislav, et al.
Publicado: (2016)

Emerging Evidence of Pathological Roles of Very-Low-Density Lipoprotein (VLDL)
por: Huang, Jih-Kai, et al.
Publicado: (2022)

Measuring VLDL(1) secretion in humans with an intravenous fat emulsion test
por: Metz, Matthäus, et al.
Publicado: (2023)

Nobiletin Attenuates VLDL Overproduction, Dyslipidemia, and Atherosclerosis in Mice With Diet-Induced Insulin Resistance
por: Mulvihill, Erin E., et al.
Publicado: (2011)

Characterization of a very-low-density lipoprotein (VLDL)-associated cytotoxic factor.
por: Chan, S. Y., et al.
Publicado: (1981)

Similar VLDL-TG Storage in Visceral and Subcutaneous Fat in Obese and Lean Women
por: Søndergaard, Esben, et al.
Publicado: (2011)

Basal and Insulin Mediated VLDL-Triglyceride Kinetics in Type 2 Diabetic Men
por: Sørensen, Lars P., et al.
Publicado: (2011)

Prandial Hypertriglyceridemia in Metabolic Syndrome Is Due to an Overproduction of Both Chylomicron and VLDL Triacylglycerol
por: Shojaee-Moradie, Fariba, et al.
Publicado: (2013)

VLDL Induced Modulation of Nitric Oxide Signalling and Cell Redox Homeostasis in HUVEC
por: Magnifico, Maria Chiara, et al.
Publicado: (2017)

Phospholipids in lipoproteins: compositional differences across VLDL, LDL, and HDL in pregnant women
por: Rauschert, Sebastian, et al.
Publicado: (2019)

Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations
por: Williams, Paul T.
Publicado: (2020)

The Differential Effects of HDL Subpopulations on Lipoprotein Lipase (LPL)-Mediated VLDL Catabolism
por: Wieczorek, Ewa, et al.
Publicado: (2021)

Lipoprotein Lipase S447X variant associated with VLDL, LDL and HDL diameter clustering in the MetS
por: Wood, Alexis C, et al.
Publicado: (2011)

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion
por: van Zwol, Willemien, et al.
Publicado: (2023)

Dose-Dependent Effect of Rosuvastatin on VLDL–Apolipoprotein C-III Kinetics in the Metabolic Syndrome
por: Ooi, Esther M.M., et al.
Publicado: (2008)

Endocytosed beta-VLDL and LDL are delivered to different intracellular vesicles in mouse peritoneal macrophages
Publicado: (1990)

Recent progress in understanding protein and lipid factors affecting hepatic VLDL assembly and secretion
por: Sundaram, Meenakshi, et al.
Publicado: (2010)

A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans
por: Timpson, Nicholas J., et al.
Publicado: (2014)

The Reelin Receptors Apolipoprotein E receptor 2 (ApoER2) and VLDL Receptor
por: Dlugosz, Paula, et al.
Publicado: (2018)

Combined LDL and VLDL Electronegativity Correlates with Coronary Heart Disease Risk in Asymptomatic Individuals
por: Shen, Ming-Yi, et al.
Publicado: (2019)

VLDL/LDL acts as a drug carrier and regulates the transport and metabolism of drugs in the body
por: Yamamoto, Hideaki, et al.
Publicado: (2017)

Genetic association of LPL rs1121923 and rs258 with plasma TG and VLDL levels
por: Al-Bustan, Suzanne A., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_49sceel04a5t8vtr1d5a8367li