Glutathione limits RUNX2 oxidation and degradation to regulate bone formation

Reactive oxygen species (ROS) are natural products of mitochondrial oxidative metabolism and oxidative protein folding. ROS levels must be well controlled, since elevated ROS has been shown to have deleterious effects on osteoblasts. Moreover, excessive ROS is thought to underlie many of the skeleta...

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Detalles Bibliográficos
Autores principales: Hu, Guoli, Yu, Yilin, Sharma, Deepika, Pruett-Miller, Shondra M., Ren, Yinshi, Zhang, Guo-Fang, Karner, Courtney M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543723/
https://www.ncbi.nlm.nih.gov/pubmed/37432749
http://dx.doi.org/10.1172/jci.insight.166888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543723/
https://www.ncbi.nlm.nih.gov/pubmed/37432749
http://dx.doi.org/10.1172/jci.insight.166888

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