Proline is increased in allergic asthma and promotes airway remodeling

Proline and its synthesis enzyme pyrroline-5-carboxylate reductase 1 (PYCR1) are implicated in epithelial-mesenchymal transition (EMT), yet how proline and PYCR1 function in allergic asthmatic airway remodeling via EMT has not yet been addressed to our knowledge. In the present study, increased leve...

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Detalles Bibliográficos
Autores principales: Xu, Tingting, Wu, Zhenzhen, Yuan, Qi, Zhang, Xijie, Liu, Yanan, Wu, Chaojie, Song, Meijuan, Wu, Jingjing, Jiang, Jingxian, Wang, Zhengxia, Chen, Zhongqi, Zhang, Mingshun, Huang, Mao, Ji, Ningfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543727/
https://www.ncbi.nlm.nih.gov/pubmed/37432745
http://dx.doi.org/10.1172/jci.insight.167395

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