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Alveolar type II epithelial cell FASN maintains lipid homeostasis in experimental COPD

Alveolar epithelial type II (AEC2) cells strictly regulate lipid metabolism to maintain surfactant synthesis. Loss of AEC2 cell function and surfactant production are implicated in the pathogenesis of the smoking-related lung disease chronic obstructive pulmonary disease (COPD). Whether smoking alte...

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Detalles Bibliográficos
Autores principales:	Fan, Li-Chao, McConn, Keith, Plataki, Maria, Kenny, Sarah, Williams, Niamh C., Kim, Kihwan, Quirke, Jennifer A., Chen, Yan, Sauler, Maor, Möbius, Matthias E., Chung, Kuei-Pin, Area Gomez, Estela, Choi, Augustine M.K., Xu, Jin-Fu, Cloonan, Suzanne M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543729/ https://www.ncbi.nlm.nih.gov/pubmed/37606038 http://dx.doi.org/10.1172/jci.insight.163403

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