Synthetic Gene Circuit-Based Assay with Multilevel Switch Enables Background-Free and Absolute Quantification of Circulating Tumor DNA

Circulating tumor DNA (ctDNA) detection has found widespread applications in tumor diagnostics and treatment, where the key is to obtain accurate quantification of ctDNA. However, this remains challenging due to the issue of background noise associated with existing assays. In this work, we develope...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Li, Zedong, Liu, Jie, Liu, Chang, Zhang, Haoqing, Lee, Won Gu, Yao, Chunyan, Guo, Hui, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543738/
https://www.ncbi.nlm.nih.gov/pubmed/37789988
http://dx.doi.org/10.34133/research.0217

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