What proportion of couples with a history of recurrent pregnancy loss and with a balanced rearrangement in one parent can potentially be identified through cell-free DNA genotyping?

BACKGROUND: Balanced chromosome aberrations are reported in about 1:30 couples with recurrent pregnancy loss (RPL). Karyotyping of both parents is necessary to identify these aberrations. Genome-wide non-invasive prenatal testing (NIPT) in case of recurrent pregnancy loss could be a more efficient w...

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Detalles Bibliográficos
Autores principales: van Zutven, Laura J. C. M., Mijalkovic, Jona, van Veghel-Plandsoen, Monique, Goense, Margaret, Polak, Marike, Knapen, Maarten F. C. M., de Weerd, Sabina, Joosten, Marieke, Diderich, Karin E. M., Hoefsloot, Lies H., Van Opstal, Diane, Srebniak, Malgorzata I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543837/
https://www.ncbi.nlm.nih.gov/pubmed/37775759
http://dx.doi.org/10.1186/s13039-023-00657-x

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