Cargando…

A registration trend in eyelid skin cancers and associated risk factors in Iran, 2005–2016

BACKGROUND: Eyelid skin cancers are the most prevalent ophthalmic malignancies. This study aimed to evaluate the association of the Human Development Index (HDI) and lifestyle risk factors with eyelid skin cancers in Iran. METHODS: This ecological study analyzed the data collected from the Iranian N...

Descripción completa

Detalles Bibliográficos
Autores principales: Safi, Sare, Ahmadzade, Mohadese, Karimi, Saeed, Akbari, Mohammad Esmaeil, Rouientan, Hamidreza, Abolhosseini, Mohammad, Rezaei Kanavi, Mozhgan, Khorrami, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543867/
https://www.ncbi.nlm.nih.gov/pubmed/37777736
http://dx.doi.org/10.1186/s12885-023-11414-z
_version_ 1785114377381216256
author Safi, Sare
Ahmadzade, Mohadese
Karimi, Saeed
Akbari, Mohammad Esmaeil
Rouientan, Hamidreza
Abolhosseini, Mohammad
Rezaei Kanavi, Mozhgan
Khorrami, Zahra
author_facet Safi, Sare
Ahmadzade, Mohadese
Karimi, Saeed
Akbari, Mohammad Esmaeil
Rouientan, Hamidreza
Abolhosseini, Mohammad
Rezaei Kanavi, Mozhgan
Khorrami, Zahra
author_sort Safi, Sare
collection PubMed
description BACKGROUND: Eyelid skin cancers are the most prevalent ophthalmic malignancies. This study aimed to evaluate the association of the Human Development Index (HDI) and lifestyle risk factors with eyelid skin cancers in Iran. METHODS: This ecological study analyzed the data collected from the Iranian National Population-based Cancer Registry (2005–2016). The data on provincial-level eyelid skin cancer risk factors were obtained from national sources. The association between provincial HDI and lifestyle risk factors with the prevalence of eyelid skin cancers was assessed. RESULTS: The mean 12-year age-standardized incidence rate (ASIR) of eyelid skin cancers was 16.22 per 100,000 (9,104 cases). The overall ASIR showed an upward trend with an estimated annual average increase of 0.006 per year. There were positive correlations between the prevalence of overall eyelid skin cancers and provincial HDI, smoking, and obesity (r = 0.32, 0.42, and 0.37, respectively). In multivariate analysis, obesity/overweight remained a positive predictor for high prevalence of total eyelid skin cancers (OR = 1.97, 95%CI = 1.08–3.58, P = 0.026), carcinoma (2.10, 1.15–3.83, P = 0.015), and basal cell carcinoma (1.48, 0.99–2.20, P = 0.054). CONCLUSIONS: An increasing trend in ASIR of eyelid skin cancers was observed in more than a decade in Iran which was positively associated with provincial HDI and prevalence of obesity. The findings of the study highlight the importance of promotional programs for preventing obesity/overweight and appropriate allocation of screening facilities based on the HDI level.
format Online
Article
Text
id pubmed-10543867
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-105438672023-10-03 A registration trend in eyelid skin cancers and associated risk factors in Iran, 2005–2016 Safi, Sare Ahmadzade, Mohadese Karimi, Saeed Akbari, Mohammad Esmaeil Rouientan, Hamidreza Abolhosseini, Mohammad Rezaei Kanavi, Mozhgan Khorrami, Zahra BMC Cancer Research BACKGROUND: Eyelid skin cancers are the most prevalent ophthalmic malignancies. This study aimed to evaluate the association of the Human Development Index (HDI) and lifestyle risk factors with eyelid skin cancers in Iran. METHODS: This ecological study analyzed the data collected from the Iranian National Population-based Cancer Registry (2005–2016). The data on provincial-level eyelid skin cancer risk factors were obtained from national sources. The association between provincial HDI and lifestyle risk factors with the prevalence of eyelid skin cancers was assessed. RESULTS: The mean 12-year age-standardized incidence rate (ASIR) of eyelid skin cancers was 16.22 per 100,000 (9,104 cases). The overall ASIR showed an upward trend with an estimated annual average increase of 0.006 per year. There were positive correlations between the prevalence of overall eyelid skin cancers and provincial HDI, smoking, and obesity (r = 0.32, 0.42, and 0.37, respectively). In multivariate analysis, obesity/overweight remained a positive predictor for high prevalence of total eyelid skin cancers (OR = 1.97, 95%CI = 1.08–3.58, P = 0.026), carcinoma (2.10, 1.15–3.83, P = 0.015), and basal cell carcinoma (1.48, 0.99–2.20, P = 0.054). CONCLUSIONS: An increasing trend in ASIR of eyelid skin cancers was observed in more than a decade in Iran which was positively associated with provincial HDI and prevalence of obesity. The findings of the study highlight the importance of promotional programs for preventing obesity/overweight and appropriate allocation of screening facilities based on the HDI level. BioMed Central 2023-09-30 /pmc/articles/PMC10543867/ /pubmed/37777736 http://dx.doi.org/10.1186/s12885-023-11414-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Safi, Sare
Ahmadzade, Mohadese
Karimi, Saeed
Akbari, Mohammad Esmaeil
Rouientan, Hamidreza
Abolhosseini, Mohammad
Rezaei Kanavi, Mozhgan
Khorrami, Zahra
A registration trend in eyelid skin cancers and associated risk factors in Iran, 2005–2016
title A registration trend in eyelid skin cancers and associated risk factors in Iran, 2005–2016
title_full A registration trend in eyelid skin cancers and associated risk factors in Iran, 2005–2016
title_fullStr A registration trend in eyelid skin cancers and associated risk factors in Iran, 2005–2016
title_full_unstemmed A registration trend in eyelid skin cancers and associated risk factors in Iran, 2005–2016
title_short A registration trend in eyelid skin cancers and associated risk factors in Iran, 2005–2016
title_sort registration trend in eyelid skin cancers and associated risk factors in iran, 2005–2016
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543867/
https://www.ncbi.nlm.nih.gov/pubmed/37777736
http://dx.doi.org/10.1186/s12885-023-11414-z
work_keys_str_mv AT safisare aregistrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT ahmadzademohadese aregistrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT karimisaeed aregistrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT akbarimohammadesmaeil aregistrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT rouientanhamidreza aregistrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT abolhosseinimohammad aregistrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT rezaeikanavimozhgan aregistrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT khorramizahra aregistrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT safisare registrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT ahmadzademohadese registrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT karimisaeed registrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT akbarimohammadesmaeil registrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT rouientanhamidreza registrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT abolhosseinimohammad registrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT rezaeikanavimozhgan registrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016
AT khorramizahra registrationtrendineyelidskincancersandassociatedriskfactorsiniran20052016