Receptor-interacting protein kinase 2 (RIPK2) profoundly contributes to post-stroke neuroinflammation and behavioral deficits with microglia as unique perpetrators

BACKGROUND: Receptor-interacting protein kinase 2 (RIPK2) is a serine/threonine kinase whose activity propagates inflammatory signaling through its association with pattern recognition receptors (PRRs) and subsequent TAK1, NF-κB, and MAPK pathway activation. After stroke, dead and dying cells releas...

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Detalles Bibliográficos
Autores principales: Larochelle, Jonathan, Tishko, Ryland J., Yang, Changjun, Ge, Yong, Phan, Leah T., Gunraj, Rachel E., Stansbury, Sofia M., Liu, Lei, Mohamadzadeh, Mansour, Khoshbouei, Habibeh, Candelario-Jalil, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543871/
https://www.ncbi.nlm.nih.gov/pubmed/37777791
http://dx.doi.org/10.1186/s12974-023-02907-6

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