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Inhibition of neutrophil extracellular trap formation ameliorates neuroinflammation and neuronal apoptosis via STING-dependent IRE1α/ASK1/JNK signaling pathway in mice with traumatic brain injury
BACKGROUND: Neuroinflammation is one of the most important pathogeneses in secondary brain injury after traumatic brain injury (TBI). Neutrophil extracellular traps (NETs) forming neutrophils were found throughout the brain tissue of TBI patients and elevated plasma NET biomarkers correlated with wo...
Autores principales: | Shi, Guihong, Liu, Liang, Cao, Yiyao, Ma, Guangshuo, Zhu, Yanlin, Xu, Jianye, Zhang, Xu, Li, Tuo, Mi, Liang, Jia, Haoran, Zhang, Yanfeng, Liu, Xilei, Zhou, Yuan, Li, Shenghui, Yang, Guili, Liu, Xiao, Chen, Fanglian, Wang, Baolong, Deng, Quanjun, Zhang, Shu, Zhang, Jianning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543875/ https://www.ncbi.nlm.nih.gov/pubmed/37777772 http://dx.doi.org/10.1186/s12974-023-02903-w |
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