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Inhibition of neutrophil extracellular trap formation ameliorates neuroinflammation and neuronal apoptosis via STING-dependent IRE1α/ASK1/JNK signaling pathway in mice with traumatic brain injury

BACKGROUND: Neuroinflammation is one of the most important pathogeneses in secondary brain injury after traumatic brain injury (TBI). Neutrophil extracellular traps (NETs) forming neutrophils were found throughout the brain tissue of TBI patients and elevated plasma NET biomarkers correlated with wo...

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Detalles Bibliográficos
Autores principales: Shi, Guihong, Liu, Liang, Cao, Yiyao, Ma, Guangshuo, Zhu, Yanlin, Xu, Jianye, Zhang, Xu, Li, Tuo, Mi, Liang, Jia, Haoran, Zhang, Yanfeng, Liu, Xilei, Zhou, Yuan, Li, Shenghui, Yang, Guili, Liu, Xiao, Chen, Fanglian, Wang, Baolong, Deng, Quanjun, Zhang, Shu, Zhang, Jianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543875/
https://www.ncbi.nlm.nih.gov/pubmed/37777772
http://dx.doi.org/10.1186/s12974-023-02903-w

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