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Prospecting for yaws in the Mbaïki Health District in the Central African Republic
INTRODUCTION: yaws is endemic in the Central African Republic. The last cases of yaws notified by CAR to WHO date back to 2012. The objective of this study was to measure the prevalence of yaws in the health district of Mbaïki and to describe its clinical and epidemiological characteristics. METHODS...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543901/ https://www.ncbi.nlm.nih.gov/pubmed/37790147 http://dx.doi.org/10.11604/pamj.2023.45.121.34060 |
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author | Piamale, Germain Bohy-Ngombet, Romaric Ghislain Zarambaud Doyama-Woza, Rodrigue Herman Fandema, Emmanuel Pamatika, Christian Maucler Dombeti, Constantin Juvénal Diemer, Henri Saint Calvaire Longo, Jean De Dieu Gresenguet, Gérard |
author_facet | Piamale, Germain Bohy-Ngombet, Romaric Ghislain Zarambaud Doyama-Woza, Rodrigue Herman Fandema, Emmanuel Pamatika, Christian Maucler Dombeti, Constantin Juvénal Diemer, Henri Saint Calvaire Longo, Jean De Dieu Gresenguet, Gérard |
author_sort | Piamale, Germain |
collection | PubMed |
description | INTRODUCTION: yaws is endemic in the Central African Republic. The last cases of yaws notified by CAR to WHO date back to 2012. The objective of this study was to measure the prevalence of yaws in the health district of Mbaïki and to describe its clinical and epidemiological characteristics. METHODS: this is a descriptive cross-sectional study, conducted from April 10 to 18, 2020 in the Mbaïki health district. Yaws cases were sought in 570 households in the 38 selected villages of the district. Any consenting individual over the age of one year with yaws-like skin lesions was a suspected case of yaws and included in the study. Blood was taken from suspected cases for serological testing (TDR, RPR and TPHA). Any suspected case of yaws with positive RPR and TPHA was considered a confirmed case. RESULTS: a total of 1967 people were examined, of whom 113 were considered suspected cases of yaws. All suspected cases were RPR-positive, 41 TPHA-positive and 13 RDT-positive. Forty-one cases of yaws were confirmed in 18 (47.37%) villages. The prevalence of yaws in the Mbaïki health district was 2.08%. Among the cases, 38.94% were children aged 1 to 14. The sex ratio was 1.69. Lesions clinically suggestive of yaws were papilloma-like in 77.00% of cases, followed by micropapules (8.00%) and ulcerations (5.00%). CONCLUSION: eight of the nine communes in the Mbaïki health district are yaws-endemic. This result suggests the need to implement the Morges strategy in the Mbaïki health district. |
format | Online Article Text |
id | pubmed-10543901 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-105439012023-10-03 Prospecting for yaws in the Mbaïki Health District in the Central African Republic Piamale, Germain Bohy-Ngombet, Romaric Ghislain Zarambaud Doyama-Woza, Rodrigue Herman Fandema, Emmanuel Pamatika, Christian Maucler Dombeti, Constantin Juvénal Diemer, Henri Saint Calvaire Longo, Jean De Dieu Gresenguet, Gérard Pan Afr Med J Research INTRODUCTION: yaws is endemic in the Central African Republic. The last cases of yaws notified by CAR to WHO date back to 2012. The objective of this study was to measure the prevalence of yaws in the health district of Mbaïki and to describe its clinical and epidemiological characteristics. METHODS: this is a descriptive cross-sectional study, conducted from April 10 to 18, 2020 in the Mbaïki health district. Yaws cases were sought in 570 households in the 38 selected villages of the district. Any consenting individual over the age of one year with yaws-like skin lesions was a suspected case of yaws and included in the study. Blood was taken from suspected cases for serological testing (TDR, RPR and TPHA). Any suspected case of yaws with positive RPR and TPHA was considered a confirmed case. RESULTS: a total of 1967 people were examined, of whom 113 were considered suspected cases of yaws. All suspected cases were RPR-positive, 41 TPHA-positive and 13 RDT-positive. Forty-one cases of yaws were confirmed in 18 (47.37%) villages. The prevalence of yaws in the Mbaïki health district was 2.08%. Among the cases, 38.94% were children aged 1 to 14. The sex ratio was 1.69. Lesions clinically suggestive of yaws were papilloma-like in 77.00% of cases, followed by micropapules (8.00%) and ulcerations (5.00%). CONCLUSION: eight of the nine communes in the Mbaïki health district are yaws-endemic. This result suggests the need to implement the Morges strategy in the Mbaïki health district. The African Field Epidemiology Network 2023-07-12 /pmc/articles/PMC10543901/ /pubmed/37790147 http://dx.doi.org/10.11604/pamj.2023.45.121.34060 Text en Copyright: Germain Piamale et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Piamale, Germain Bohy-Ngombet, Romaric Ghislain Zarambaud Doyama-Woza, Rodrigue Herman Fandema, Emmanuel Pamatika, Christian Maucler Dombeti, Constantin Juvénal Diemer, Henri Saint Calvaire Longo, Jean De Dieu Gresenguet, Gérard Prospecting for yaws in the Mbaïki Health District in the Central African Republic |
title | Prospecting for yaws in the Mbaïki Health District in the Central African Republic |
title_full | Prospecting for yaws in the Mbaïki Health District in the Central African Republic |
title_fullStr | Prospecting for yaws in the Mbaïki Health District in the Central African Republic |
title_full_unstemmed | Prospecting for yaws in the Mbaïki Health District in the Central African Republic |
title_short | Prospecting for yaws in the Mbaïki Health District in the Central African Republic |
title_sort | prospecting for yaws in the mbaïki health district in the central african republic |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543901/ https://www.ncbi.nlm.nih.gov/pubmed/37790147 http://dx.doi.org/10.11604/pamj.2023.45.121.34060 |
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