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Pharmacokinetic analysis of acute and dietary exposure to piperonyl butoxide in the mouse

Piperonyl butoxide (PBO) is a popular insecticide synergist present in thousands of commercial, agricultural, and household products. PBO inhibits cytochrome P450 activity, impairing the ability of insects to detoxify insecticides. PBO was recently discovered to also inhibit Sonic hedgehog signaling...

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Detalles Bibliográficos
Autores principales:	Jenkins, Alyssa E., Scarlett, Cameron O., Beames, Tyler G., Rivera-González, Kenneth S., Martin, Alexander A., Sun, Miranda R., Hutson, Paul R., Lipinski, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543969/ https://www.ncbi.nlm.nih.gov/pubmed/37789951 http://dx.doi.org/10.1016/j.toxrep.2023.09.017

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