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Nanoscopic Elucidation of Spontaneous Self-Assembly of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Open Reading Frame 6 (ORF6) Protein

[Image: see text] Open reading frame 6 (ORF6), the accessory protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that suppresses host type-I interferon signaling, possesses amyloidogenic sequences. ORF6 amyloidogenic peptides self-assemble to produce cytotoxic amyloid fibrils. Cu...

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Detalles Bibliográficos
Autores principales:	Nishide, Goro, Lim, Keesiang, Tamura, Maiki, Kobayashi, Akiko, Zhao, Qingci, Hazawa, Masaharu, Ando, Toshio, Nishida, Noritaka, Wong, Richard W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544025/ https://www.ncbi.nlm.nih.gov/pubmed/37707320 http://dx.doi.org/10.1021/acs.jpclett.3c01440

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