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c-Kit Receptors as a Therapeutic Target in Cancer: Current Insights

c-Kit is a type III receptor tyrosine kinase (RTK) that has an essential role in various biological functions including gametogenesis, melanogenesis, hematopoiesis, cell survival, and apoptosis. c-KIT aberrations, either overexpression or loss-of-function mutations, have been implicated in the patho...

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Detalles Bibliográficos
Autores principales: Abdellateif, Mona S, Bayoumi, Ahmed K, Mohammed, Mohammed Aly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544070/
https://www.ncbi.nlm.nih.gov/pubmed/37790582
http://dx.doi.org/10.2147/OTT.S404648

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