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c-Kit Receptors as a Therapeutic Target in Cancer: Current Insights
c-Kit is a type III receptor tyrosine kinase (RTK) that has an essential role in various biological functions including gametogenesis, melanogenesis, hematopoiesis, cell survival, and apoptosis. c-KIT aberrations, either overexpression or loss-of-function mutations, have been implicated in the patho...
Autores principales: | Abdellateif, Mona S, Bayoumi, Ahmed K, Mohammed, Mohammed Aly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544070/ https://www.ncbi.nlm.nih.gov/pubmed/37790582 http://dx.doi.org/10.2147/OTT.S404648 |
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