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Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis

Polyphenols are the main component of Phyllanthus emblica (PE). However, polyphenols are so easy to transform that it is unknown that how drying methods driven by heating affect the anti-fatigue effect of PE. This manuscript investigated the effects of five drying methods on the chemical composition...

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Detalles Bibliográficos
Autores principales: Zhang, Dingkun, Deng, Xuan, Li, Mengqi, Qiu, Min, Zhang, Yifan, Li, Gefei, Jiang, Yurou, Tan, Peng, Fan, Sanhu, Zheng, Youde, Lin, Junzhi, Han, Li, Huang, Haozhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544184/
https://www.ncbi.nlm.nih.gov/pubmed/37779204
http://dx.doi.org/10.1186/s13020-023-00835-4
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author Zhang, Dingkun
Deng, Xuan
Li, Mengqi
Qiu, Min
Zhang, Yifan
Li, Gefei
Jiang, Yurou
Tan, Peng
Fan, Sanhu
Zheng, Youde
Lin, Junzhi
Han, Li
Huang, Haozhou
author_facet Zhang, Dingkun
Deng, Xuan
Li, Mengqi
Qiu, Min
Zhang, Yifan
Li, Gefei
Jiang, Yurou
Tan, Peng
Fan, Sanhu
Zheng, Youde
Lin, Junzhi
Han, Li
Huang, Haozhou
author_sort Zhang, Dingkun
collection PubMed
description Polyphenols are the main component of Phyllanthus emblica (PE). However, polyphenols are so easy to transform that it is unknown that how drying methods driven by heating affect the anti-fatigue effect of PE. This manuscript investigated the effects of five drying methods on the chemical composition transformation and anti-fatigue of PE, and discussed the action mechanism. The results suggested that the anti-fatigue effect of PE with hot-air-dried at 100 °C was the best, which was as 1.63 times as that with freeze-drying. Ellagic acid (EA) may be a key component of PE in anti-fatigue, and its mechanism of action may be related to regulating intestinal microbiota, protecting mitochondria, and regulating energy metabolism. This study first revealed the thermal transformation of polyphenols in PE, found the most effective strategy for enhancing the anti-fatigue function, and explores its action mechanism. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13020-023-00835-4.
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spelling pubmed-105441842023-10-03 Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis Zhang, Dingkun Deng, Xuan Li, Mengqi Qiu, Min Zhang, Yifan Li, Gefei Jiang, Yurou Tan, Peng Fan, Sanhu Zheng, Youde Lin, Junzhi Han, Li Huang, Haozhou Chin Med Research Polyphenols are the main component of Phyllanthus emblica (PE). However, polyphenols are so easy to transform that it is unknown that how drying methods driven by heating affect the anti-fatigue effect of PE. This manuscript investigated the effects of five drying methods on the chemical composition transformation and anti-fatigue of PE, and discussed the action mechanism. The results suggested that the anti-fatigue effect of PE with hot-air-dried at 100 °C was the best, which was as 1.63 times as that with freeze-drying. Ellagic acid (EA) may be a key component of PE in anti-fatigue, and its mechanism of action may be related to regulating intestinal microbiota, protecting mitochondria, and regulating energy metabolism. This study first revealed the thermal transformation of polyphenols in PE, found the most effective strategy for enhancing the anti-fatigue function, and explores its action mechanism. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13020-023-00835-4. BioMed Central 2023-10-01 /pmc/articles/PMC10544184/ /pubmed/37779204 http://dx.doi.org/10.1186/s13020-023-00835-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zhang, Dingkun
Deng, Xuan
Li, Mengqi
Qiu, Min
Zhang, Yifan
Li, Gefei
Jiang, Yurou
Tan, Peng
Fan, Sanhu
Zheng, Youde
Lin, Junzhi
Han, Li
Huang, Haozhou
Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis
title Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis
title_full Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis
title_fullStr Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis
title_full_unstemmed Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis
title_short Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis
title_sort thermal treatment enhances the resisting exercise fatigue effect of phyllanthus emblica l.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544184/
https://www.ncbi.nlm.nih.gov/pubmed/37779204
http://dx.doi.org/10.1186/s13020-023-00835-4
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