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Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis
Polyphenols are the main component of Phyllanthus emblica (PE). However, polyphenols are so easy to transform that it is unknown that how drying methods driven by heating affect the anti-fatigue effect of PE. This manuscript investigated the effects of five drying methods on the chemical composition...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544184/ https://www.ncbi.nlm.nih.gov/pubmed/37779204 http://dx.doi.org/10.1186/s13020-023-00835-4 |
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author | Zhang, Dingkun Deng, Xuan Li, Mengqi Qiu, Min Zhang, Yifan Li, Gefei Jiang, Yurou Tan, Peng Fan, Sanhu Zheng, Youde Lin, Junzhi Han, Li Huang, Haozhou |
author_facet | Zhang, Dingkun Deng, Xuan Li, Mengqi Qiu, Min Zhang, Yifan Li, Gefei Jiang, Yurou Tan, Peng Fan, Sanhu Zheng, Youde Lin, Junzhi Han, Li Huang, Haozhou |
author_sort | Zhang, Dingkun |
collection | PubMed |
description | Polyphenols are the main component of Phyllanthus emblica (PE). However, polyphenols are so easy to transform that it is unknown that how drying methods driven by heating affect the anti-fatigue effect of PE. This manuscript investigated the effects of five drying methods on the chemical composition transformation and anti-fatigue of PE, and discussed the action mechanism. The results suggested that the anti-fatigue effect of PE with hot-air-dried at 100 °C was the best, which was as 1.63 times as that with freeze-drying. Ellagic acid (EA) may be a key component of PE in anti-fatigue, and its mechanism of action may be related to regulating intestinal microbiota, protecting mitochondria, and regulating energy metabolism. This study first revealed the thermal transformation of polyphenols in PE, found the most effective strategy for enhancing the anti-fatigue function, and explores its action mechanism. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13020-023-00835-4. |
format | Online Article Text |
id | pubmed-10544184 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-105441842023-10-03 Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis Zhang, Dingkun Deng, Xuan Li, Mengqi Qiu, Min Zhang, Yifan Li, Gefei Jiang, Yurou Tan, Peng Fan, Sanhu Zheng, Youde Lin, Junzhi Han, Li Huang, Haozhou Chin Med Research Polyphenols are the main component of Phyllanthus emblica (PE). However, polyphenols are so easy to transform that it is unknown that how drying methods driven by heating affect the anti-fatigue effect of PE. This manuscript investigated the effects of five drying methods on the chemical composition transformation and anti-fatigue of PE, and discussed the action mechanism. The results suggested that the anti-fatigue effect of PE with hot-air-dried at 100 °C was the best, which was as 1.63 times as that with freeze-drying. Ellagic acid (EA) may be a key component of PE in anti-fatigue, and its mechanism of action may be related to regulating intestinal microbiota, protecting mitochondria, and regulating energy metabolism. This study first revealed the thermal transformation of polyphenols in PE, found the most effective strategy for enhancing the anti-fatigue function, and explores its action mechanism. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13020-023-00835-4. BioMed Central 2023-10-01 /pmc/articles/PMC10544184/ /pubmed/37779204 http://dx.doi.org/10.1186/s13020-023-00835-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Zhang, Dingkun Deng, Xuan Li, Mengqi Qiu, Min Zhang, Yifan Li, Gefei Jiang, Yurou Tan, Peng Fan, Sanhu Zheng, Youde Lin, Junzhi Han, Li Huang, Haozhou Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis |
title | Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis |
title_full | Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis |
title_fullStr | Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis |
title_full_unstemmed | Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis |
title_short | Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis |
title_sort | thermal treatment enhances the resisting exercise fatigue effect of phyllanthus emblica l.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544184/ https://www.ncbi.nlm.nih.gov/pubmed/37779204 http://dx.doi.org/10.1186/s13020-023-00835-4 |
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