Tyrosine kinase signaling-independent MET-targeting with CAR-T cells

BACKGROUND: Recent progress in cancer immunotherapy encourages the expansion of chimeric antigen receptor (CAR) T cell therapy in solid tumors including hepatocellular carcinoma (HCC). Overexpression of MET receptor tyrosine kinase is common in HCC; however, MET inhibitors are effective only when ME...

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Detalles Bibliográficos
Autores principales: Qin, Anna, Qin, Yuan, Lee, Joseph, Musket, Anna, Ying, Mingyao, Krenciute, Giedre, Marincola, Francesco M., Yao, Zhi Q., Musich, Phillip R., Xie, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544186/
https://www.ncbi.nlm.nih.gov/pubmed/37779207
http://dx.doi.org/10.1186/s12967-023-04521-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544186/
https://www.ncbi.nlm.nih.gov/pubmed/37779207
http://dx.doi.org/10.1186/s12967-023-04521-9

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