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TDP-43 pathology is associated with increased tau burdens and seeding

BACKGROUND: Most Alzheimer’s Disease (AD) cases also exhibit limbic predominant age-related TDP-43 encephalopathy neuropathological changes (LATE-NC), besides amyloid-β plaques and neurofibrillary tangles (NFTs) containing hyperphosphorylated tau (p-tau). LATE-NC is characterized by cytoplasmic aggr...

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Detalles Bibliográficos
Autores principales:	Tomé, Sandra O., Tsaka, Grigoria, Ronisz, Alicja, Ospitalieri, Simona, Gawor, Klara, Gomes, Luis Aragão, Otto, Markus, von Arnim, Christine A. F., Van Damme, Philip, Van Den Bosch, Ludo, Ghebremedhin, Estifanos, Laureyssen, Celeste, Sleegers, Kristel, Vandenberghe, Rik, Rousseau, Frederic, Schymkowitz, Joost, Thal, Dietmar Rudolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544192/ https://www.ncbi.nlm.nih.gov/pubmed/37777806 http://dx.doi.org/10.1186/s13024-023-00653-0

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