PGC-1α–mediated angiogenesis prevents pulmonary hypertension in mice

Pulmonary hypertension (PH) is a life-threatening disease characterized by a progressive narrowing of pulmonary arterioles. Although VEGF is highly expressed in lung of patients with PH and in animal PH models, the involvement of angiogenesis remains elusive. To clarify the pathophysiological functi...

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Detalles Bibliográficos
Autores principales: Fujiwara, Takayuki, Takeda, Norifumi, Hara, Hironori, Ishii, Satoshi, Numata, Genri, Tokiwa, Hiroyuki, Katoh, Manami, Maemura, Sonoko, Suzuki, Takaaki, Takiguchi, Hiroshi, Yanase, Tomonobu, Kubota, Yoshiaki, Nomura, Seitaro, Hatano, Masaru, Ueda, Kazutaka, Harada, Mutsuo, Toko, Haruhiro, Takimoto, Eiki, Akazawa, Hiroshi, Morita, Hiroyuki, Nishimura, Satoshi, Komuro, Issei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544206/
https://www.ncbi.nlm.nih.gov/pubmed/37681410
http://dx.doi.org/10.1172/jci.insight.162632

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