Cargando…

1,25-Dihydroxyvitamin D(3) regulates furin-mediated FGF23 cleavage

Intact fibroblast growth factor 23 (iFGF23) is a phosphaturic hormone that is cleaved by furin into N-terminal and C-terminal fragments. Several studies have implicated vitamin D in regulating furin in infections. Thus, we investigated the effect of 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D] and the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Han, Bastepe, Isinsu, Zhou, Wen, Ay, Birol, Ceraj, Zara, Portales-Castillo, Ignacio A., Liu, Eva S., Burnett-Bowie, Sherri-Ann M., Jüppner, Harald, Rhee, Eugene P., Bastepe, Murat, Simic, Petra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544208/ https://www.ncbi.nlm.nih.gov/pubmed/37681408 http://dx.doi.org/10.1172/jci.insight.168957

Ejemplares similares

The long-range interaction between two GNAS imprinting control regions delineates pseudohypoparathyroidism type 1B pathogenesis
por: Iwasaki, Yorihiro, et al.
Publicado: (2023)

The GNAS Locus: Quintessential Complex Gene Encoding Gsα, XLαs, and other Imprinted Transcripts
por: Bastepe, Murat
Publicado: (2007)

Maternal GNAS Contributes to the Extra-Large G Protein α-Subunit (XLαs) Expression in a Cell Type-Specific Manner
por: Cui, Quixia, et al.
Publicado: (2021)

Long-Term Clinical Outcome and Carrier Phenotype in Autosomal Recessive Hypophosphatemia Caused by a Novel DMP1 Mutation
por: Mäkitie, Outi, et al.
Publicado: (2010)

Vitamin D, 1,25-Dihydroxyvitamin D, FGF23, and Graft Function after Renal Transplantation
por: Mehrotra, Sonia, et al.
Publicado: (2019)

Furin cleavage sites naturally occur in coronaviruses
por: Wu, Yiran, et al.
Publicado: (2021)

MON-LB087 Synthesis of Osteocyte-Derived Phosphaturic Hormone FGF23 via IP3/PKC Signaling Downstream of the Extra-Large Gα Subunit (XLαs)
por: He, Qing, et al.
Publicado: (2019)

Phosphate and FGF-23
por: Jüppner, Harald
Publicado: (2011)

Investigation on the processing and improving the cleavage efficiency of furin cleavage sites in Pichia pastoris
por: Huang, Yide, et al.
Publicado: (2018)

Global Diversification and Distribution of Coronaviruses With Furin Cleavage Sites
por: Liu, Xiaotong, et al.
Publicado: (2021)

Single-cell RNA sequencing identifies Fgf23-expressing osteocytes in response to 1,25-dihydroxyvitamin D(3) treatment
por: Hanai, Ayako, et al.
Publicado: (2023)

FurinDB: A Database of 20-Residue Furin Cleavage Site Motifs, Substrates and Their Associated Drugs
por: Tian, Sun, et al.
Publicado: (2011)

SARS-CoV-2 furin cleavage site was not engineered
por: Garry, Robert F.
Publicado: (2022)

Sporadic Pseudohypoparathyroidism Type 1B in Monozygotic Twins: Insights Into the Pathogenesis of Methylation Defects
por: Keidai, Yamato, et al.
Publicado: (2021)

Sporadic Pseudohypoparathyroidism 1B in Monozygotic Twins: Insights Into the Pathogenesis of Methylation Defects
por: Keidai, Yamato, et al.
Publicado: (2021)

THU233 Reduction Of Overutilization Of 1,25-Dihydroxyvitamin D
por: Brown, Jeremy, et al.
Publicado: (2023)

Serum FGF23 levels may not be associated with serum phosphate and 1,25-dihydroxyvitamin D levels in patients with Fanconi syndrome–induced hypophosphatemia
por: Goto, Shunsuke, et al.
Publicado: (2016)

Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis
por: Johnson, Bryan A., et al.
Publicado: (2020)

Heparin enhances the furin cleavage of HIV‐1 gp160 peptides
por: Pasquato, A., et al.
Publicado: (2007)

Cleavage mechanism of the H5N1 hemagglutinin by trypsin and furin
por: Guo, X.-L., et al.
Publicado: (2008)

The Emergence of the Spike Furin Cleavage Site in SARS-CoV-2
por: Chan, Yujia Alina, et al.
Publicado: (2021)

Serum 1,25-Dihydroxyvitamin D: An Outcome Prognosticator in Human Sepsis
por: Nguyen, H. Bryant, et al.
Publicado: (2013)

Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System
por: Faye, Pierre Antoine, et al.
Publicado: (2019)

High-Resolution Analysis and Functional Mapping of Cleavage Sites and Substrate Proteins of Furin in the Human Proteome
por: Shiryaev, Sergey A., et al.
Publicado: (2013)

Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation
por: Zhang, Liping, et al.
Publicado: (2021)

Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation
por: Zhang, Liping, et al.
Publicado: (2021)

SARS-CoV-2 spike and its adaptable furin cleavage site
por: Whittaker, Gary R
Publicado: (2021)

Genomic determinants of Furin cleavage in diverse European SARS-related bat coronaviruses
por: Sander, Anna-Lena, et al.
Publicado: (2022)

A novel bat coronavirus with a polybasic furin-like cleavage site
por: Zhu, Wentao, et al.
Publicado: (2023)

MON-374 Management of 1,25-dihydroxyvitamin D (1,25-OHD) Mediated Hypercalcemia of Unknown Etiology
por: Menon, Sruthi, et al.
Publicado: (2020)

A naturally occurring membrane-anchored Gα(s) variant, XLα(s), activates phospholipase Cβ4
por: Phan, Hoa T.N., et al.
Publicado: (2022)

Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3
por: Halicka, H. Dorota, et al.
Publicado: (2012)

The relationship of 1,25-dihydroxyvitamin D and Vitamin D binding protein in periodontitis
por: Rafique, Sara, et al.
Publicado: (2019)

Mechanistic study of the cause of decreased blood 1,25-Dihydroxyvitamin D in sepsis
por: Li, Chih-Huang, et al.
Publicado: (2019)

1,25-dihydroxyvitamin D deficiency is independently associated with cardiac valve calcification in patients with chronic kidney disease
por: Kim, Il Young, et al.
Publicado: (2022)

A Novel T55A Variant of G(s) α Associated with Impaired cAMP Production, Bone Fragility, and Osteolysis
por: Wentworth, Kelly, et al.
Publicado: (2016)

8-Cl-Adenosine enhances 1,25-dihydroxyvitamin D(3)-induced growth inhibition without affecting 1,25-dihydroxyvitamin D(3)-stimulated differentiation of primary mouse epidermal keratinocytes
por: Bollag, Wendy B, et al.
Publicado: (2004)

Protection of the Furin Cleavage Site in Low-Toxicity Immunotoxins Based on Pseudomonas Exotoxin A
por: Kaplan, Gilad, et al.
Publicado: (2016)

The N terminus of α-ENaC mediates ENaC cleavage and activation by furin
por: Kota, Pradeep, et al.
Publicado: (2018)

The SARS-CoV-2 furin cleavage site: natural selection or smoking gun?
por: Lubinski, Bailey, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7hc0prifnpfsr64a6a10sa5ab7