Vascular smooth muscle–specific YAP/TAZ deletion triggers aneurysm development in mouse aorta

Inadequate adaption to mechanical forces, including blood pressure, contributes to development of arterial aneurysms. Recent studies have pointed to a mechanoprotective role of YAP and TAZ in vascular smooth muscle cells (SMCs). Here, we identified reduced expression of YAP1 in human aortic aneurysm...

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Detalles Bibliográficos
Autores principales: Arévalo Martínez, Marycarmen, Ritsvall, Olivia, Bastrup, Joakim Armstrong, Celik, Selvi, Jakobsson, Gabriel, Daoud, Fatima, Winqvist, Christopher, Aspberg, Anders, Rippe, Catarina, Maegdefessel, Lars, Schiopu, Alexandru, Jepps, Thomas A., Holmberg, Johan, Swärd, Karl, Albinsson, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544211/
https://www.ncbi.nlm.nih.gov/pubmed/37561588
http://dx.doi.org/10.1172/jci.insight.170845

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