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FLARE: a fast and flexible workflow for identifying RNA editing foci

BACKGROUND: Fusion of RNA-binding proteins (RBPs) to RNA base-editing enzymes (such as APOBEC1 or ADAR) has emerged as a powerful tool for the discovery of RBP binding sites. However, current methods that analyze sequencing data from RNA-base editing experiments are vulnerable to false positives due...

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Detalles Bibliográficos
Autores principales: Kofman, Eric, Yee, Brian, Medina-Munoz, Hugo C., Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544219/
https://www.ncbi.nlm.nih.gov/pubmed/37784060
http://dx.doi.org/10.1186/s12859-023-05452-4