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Hepatorenal pathologies in TNF-transgenic mouse model of rheumatoid arthritis are alleviated by anti-TNF treatment

OBJECTIVE: To examine and quantify liver and kidney lesions and their response to anti-tumor necrosis factor (TNF) therapy in a TNF-Tg mouse model of rheumatoid arthritis (RA). METHODS: Female TNF-Tg (Tg3647) mice were used as the animal model for chronic RA. Ultrasound, immunofluorescence, histolog...

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Detalles Bibliográficos
Autores principales: Li, Xuefei, Wang, Yi, Chen, Ziqiang, Ruan, Ming, Yang, Can, Zhou, Maolin, Li, Ning, Xing, Lianping, Xu, Hao, Yang, Ling, Shi, Qi, Wang, Yongjun, Chen, Jinman, Liang, Qianqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544221/
https://www.ncbi.nlm.nih.gov/pubmed/37784156
http://dx.doi.org/10.1186/s13075-023-03178-5