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Loss of Farnesoid X receptor (FXR) accelerates dysregulated glucose and renal injury in db/db mice

BACKGROUND: End-stage renal disease is primarily caused by diabetic kidney disease (DKD). The Farnesoid X receptor (FXR), a member of the nuclear receptor superfamily, has anti-inflammatory, lipid-lowering and hypoglycemic properties. It also inhibits renal fibrosis. Although its physiological role...

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Detalles Bibliográficos
Autores principales:	Qiu, Yuxiang, Kang, Ningsu, Wang, Xi, Yao, Yao, Cui, Jun, Zhang, Xiaoyan, Zheng, Lu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2023
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544308/ https://www.ncbi.nlm.nih.gov/pubmed/37790634 http://dx.doi.org/10.7717/peerj.16155

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