Cargando…

Potential molecular targets and drugs for basement membranes-related intervertebral disk degeneration through bioinformatics analysis and molecular docking

BACKGROUND: Through bioinformatics analysis to identify the hub genes of Intervertebral disc degeneration (IVDD) associated with basement membranes (BMs) and find out the potential molecular targets and drugs for BMs-related annulus fibrosus (AF) degeneration based on bioinformatic analysis and mole...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Zelin, Qin, Weicheng, Zhang, Peng, He, Jiahui, Cheng, Zhaojun, Gong, Yan, Zhu, Guangye, Liang, De, Ren, Hui, Jiang, Xiaobing, Sun, Yuping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544312/ https://www.ncbi.nlm.nih.gov/pubmed/37784117 http://dx.doi.org/10.1186/s12891-023-06891-z

Ejemplares similares

Antioxidative nanofullerol prevents intervertebral disk degeneration
por: Yang, Xinlin, et al.
Publicado: (2014)

Mechanobiology of MicroRNAs in Intervertebral Disk Degeneration
por: Supra, Rajiv, et al.
Publicado: (2023)

Identification of a potential novel biomarker in intervertebral disk degeneration by bioinformatics analysis and experimental validation
por: Yang, Zhao, et al.
Publicado: (2023)

Inflammatory Mediators in Intervertebral Disk Degeneration and Discogenic Pain
por: Wuertz, Karin, et al.
Publicado: (2013)

Circular RNAs in compression-induced intervertebral disk degeneration
por: Chen, Ximiao, et al.
Publicado: (2020)

Intervertebral Disk Degeneration: The Microenvironment and Tissue Engineering Strategies
por: Dou, Yiming, et al.
Publicado: (2021)

Cytokine Imbalance as a Biomarker of Intervertebral Disk Degeneration
por: Shnayder, Natalia A., et al.
Publicado: (2023)

FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration
por: Alvarez‐Garcia, Oscar, et al.
Publicado: (2018)

Molecular Therapy for Disk Degeneration and Pain
por: Mwale, Fackson
Publicado: (2013)

Effect of percutaneous nucleoplasty with coblation on phospholipase A2 activity in the intervertebral disks of an animal model of intervertebral disk degeneration: a randomized controlled trial
por: Ren, Dajiang, et al.
Publicado: (2015)

Mechanisms of Intervertebral Disk Degeneration/Injury and Pain: A Review
por: Ito, Keita, et al.
Publicado: (2013)

Anterior Limbus Vertebra and Intervertebral Disk Degeneration in Japanese Collegiate Gymnasts
por: Koyama, Koji, et al.
Publicado: (2013)

Association Between VDR FokI Polymorphism and Intervertebral Disk Degeneration
por: Zhao, Jian, et al.
Publicado: (2015)

Spatial mapping of collagen content and structure in human intervertebral disk degeneration
por: Zeldin, Lawrence, et al.
Publicado: (2020)

Expression of metalloproteinases and their inhibitors in degenerated and extruded intervertebral disks in chondrodystrophic dogs
por: ISHINO, Hirokazu, et al.
Publicado: (2021)

Influence of Age and Gender on Intervertebral Disk Degeneration and Height in the Thoracolumbar Spine
por: Machino, Masaaki, et al.
Publicado: (2021)

Mechanisms of Intervertebral Disc Degeneration Treatment with Deer Antlers Based on Network Pharmacology and Molecular Docking
por: Weng, Rui, et al.
Publicado: (2022)

Molecular Mechanisms of Intervertebral Disc Degeneration
por: Rider, Sean M., et al.
Publicado: (2018)

Intervertebral Disk Degeneration in Rabbits: Histomorphometric and Histomorphological Effects of Aloe Vera Gel
por: Akinola, Busuyi Kolade, et al.
Publicado: (2020)

Current Progress in the Endogenous Repair of Intervertebral Disk Degeneration Based on Progenitor Cells
por: Zhang, Yanbin, et al.
Publicado: (2021)

MiR-206 improves intervertebral disk degeneration by targeting GJA1
por: Zhou, Peng, et al.
Publicado: (2022)

Does Calcium Phosphate Cement Kyphoplasty Cause Intervertebral Disk Degeneration in Adolescents?
por: Tschauner, Sebastian, et al.
Publicado: (2022)

Lower Plasma Melatonin in the Intervertebral Disk Degeneration Patients Was Associated with Increased Proinflammatory Cytokines
por: Tian, Yixing, et al.
Publicado: (2021)

Low expression of miR-142-3p promotes intervertebral disk degeneration
por: Xue, Jianmin, et al.
Publicado: (2021)

Melatonin Attenuates Intervertebral Disk Degeneration via Maintaining Cartilaginous Endplate Integrity in Rats
por: Wu, Xiexing, et al.
Publicado: (2021)

Intervertebral disk diseases : causes, diagnosis, treatment and prophylaxis /
por: Krämer, Jürgen, 1939-
Publicado: (1981)

Novel Imaging of the Intervertebral Disk and Pain
por: Fenty, Matthew, et al.
Publicado: (2013)

The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain
por: Kim, Jae-Sung, et al.
Publicado: (2011)

Implications for a Stem Cell Regenerative Medicine Based Approach to Human Intervertebral Disk Degeneration
por: Kraus, Petra, et al.
Publicado: (2017)

The role of miRNA, lncRNA and circRNA in the development of intervertebral disk degeneration (Review)
por: Jiang, Jian, et al.
Publicado: (2021)

MiR-330-5p inhibits intervertebral disk degeneration via targeting CILP
por: Li, Shangzhi, et al.
Publicado: (2021)

Research on the Mechanism of Kaempferol for Treating Senile Osteoporosis by Network Pharmacology and Molecular Docking
por: Tang, Fuyu, et al.
Publicado: (2022)

Localization of peripherin/rds in the disk membranes of cone and rod photoreceptors: relationship to disk membrane morphogenesis and retinal degeneration
Publicado: (1992)

Correlation among Inflammatory Cytokine Expression Levels, Degree of Disk Degeneration, and Predominant Clinical Symptoms in Patients with Degenerated Intervertebral Discs
por: Sainoh, Takeshi, et al.
Publicado: (2017)

Theoretical Explorations Generate New Hypotheses About the Role of the Cartilage Endplate in Early Intervertebral Disk Degeneration
por: Ruiz Wills, Carlos, et al.
Publicado: (2018)

Advances and Prospects in Biomaterials for Intervertebral Disk Regeneration
por: Li, Chunxu, et al.
Publicado: (2021)

STUDIES OF MOLECULAR CHANGES IN INTERVERTEBRAL DISC DEGENERATION IN ANIMAL MODEL
por: de Campos, Marcelo Ferraz, et al.
Publicado: (2016)

Molecular mechanisms of cell death in intervertebral disc degeneration (Review)
por: ZHANG, FAN, et al.
Publicado: (2016)

Disk Degeneration and Pain
por: Samartzis, Dino, et al.
Publicado: (2013)

Intervertebral disk width in dogs with and without clinical signs of disk associated cervical spondylomyelopathy
por: De Decker, Steven, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_pcntfs5ih49u6qkc5reuecocng