scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal cancer cells

Colorectal cancer (CRC) is one of the deadliest cancers worldwide, with the 5 year survival rate in metastatic cases limited to 12%. The design of targeted and effective therapeutics remains a major unmet clinical need in CRC treatment. Carcinoembryonic antigen (CEA), a glycoprotein overexpressed in...

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Detalles Bibliográficos
Autores principales: Silveira, Maria José, Martins, Cláudia, Cruz, Tânia, Castro, Flávia, Amorim-Costa, Ângela, Chester, Kerry, Oliveira, Maria José, Sarmento, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544461/
https://www.ncbi.nlm.nih.gov/pubmed/37784150
http://dx.doi.org/10.1186/s12951-023-02126-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544461/
https://www.ncbi.nlm.nih.gov/pubmed/37784150
http://dx.doi.org/10.1186/s12951-023-02126-4

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