Novel quantitative immunohistochemical analysis for evaluating PD-L1 expression with phosphor-integrated dots for predicting the efficacy of patients with cancer treated with immune checkpoint inhibitors

INTRODUCTION: Programmed cell death ligand 1 (PD-L1) expression in tumor tissues is measured as a predictor of the therapeutic efficacy of immune checkpoint inhibitors (ICIs) in many cancer types. PD-L1 expression is evaluated by immunohistochemical staining using 3,3´-diaminobenzidine (DAB) chronog...

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Detalles Bibliográficos
Autores principales: Ohkuma, Ryotaro, Miura, Sakiko, Muto, Satoshi, Toyomasu, Yoshitaka, Fujimoto, Yuki, Ieguchi, Katsuaki, Onishi, Nobuyuki, Shimizu, Takashi, Watanabe, Makoto, Takayanagi, Daisuke, Goshima, Tsubasa, Horiike, Atsushi, Hamada, Kazuyuki, Ariizumi, Hirotsugu, Shimokawa, Masahiro, Hirasawa, Yuya, Ishiguro, Tomoyuki, Suzuki, Risako, Iriguchi, Nana, Tsurui, Toshiaki, Mura, Emiko, Takenoshita, Sachiko, Numajiri, Kazuki, Okabe, Naoyuki, Yoshimura, Kiyoshi, Tsuji, Mayumi, Kiuchi, Yuji, Yajima, Toshiki, Ishida, Hideyuki, Suzuki, Hiroyuki, Yamochi, Toshiko, Kobayashi, Shinichi, Tsunoda, Takuya, Wada, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544572/
https://www.ncbi.nlm.nih.gov/pubmed/37790929
http://dx.doi.org/10.3389/fimmu.2023.1260492

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