Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia infection

INTRODUCTION: Streptococcus pneumoniae is one of the main causes of community-acquired infections in the lung alveoli in children and the elderly. Alveolar macrophages (AM) patrol alveoli in homeostasis and under infectious conditions. However, the molecular adaptations of AM upon infections with St...

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Detalles Bibliográficos
Autores principales: Zec, Kristina, Thiebes, Stephanie, Bottek, Jenny, Siemes, Devon, Spangenberg, Philippa, Trieu, Duc Viet, Kirstein, Nils, Subramaniam, Nirojah, Christ, Robin, Klein, Diana, Jendrossek, Verena, Loose, Maria, Wagenlehner, Florian, Jablonska, Jadwiga, Bracht, Thilo, Sitek, Barbara, Budeus, Bettina, Klein-Hitpass, Ludger, Theegarten, Dirk, Shevchuk, Olga, Engel, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544576/
https://www.ncbi.nlm.nih.gov/pubmed/37790937
http://dx.doi.org/10.3389/fimmu.2023.1227191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544576/
https://www.ncbi.nlm.nih.gov/pubmed/37790937
http://dx.doi.org/10.3389/fimmu.2023.1227191

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