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Drug-Resistant Parkinson’s Disease in a Patient With Hereditary Hemochromatosis: A Case Report

A 55-year-old male, with a strong family history of hereditary hemochromatosis, presented with progressively worsening right-sided tremor and Parkinsonian symptoms. He was diagnosed with hereditary hemochromatosis based on genetic testing and started undergoing regular phlebotomies to reduce his blo...

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Autores principales: Banta, Conor W, Zonna, Xavier, Lott, Ronald, Jaisawal, Pooja, Elsisi, Amr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544707/
https://www.ncbi.nlm.nih.gov/pubmed/37790065
http://dx.doi.org/10.7759/cureus.44530
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author Banta, Conor W
Zonna, Xavier
Lott, Ronald
Jaisawal, Pooja
Elsisi, Amr
author_facet Banta, Conor W
Zonna, Xavier
Lott, Ronald
Jaisawal, Pooja
Elsisi, Amr
author_sort Banta, Conor W
collection PubMed
description A 55-year-old male, with a strong family history of hereditary hemochromatosis, presented with progressively worsening right-sided tremor and Parkinsonian symptoms. He was diagnosed with hereditary hemochromatosis based on genetic testing and started undergoing regular phlebotomies to reduce his blood iron levels. Despite extensive trials of different pharmaceutical therapies, including levodopa-carbidopa, his Parkinsonian symptoms were not relieved and continued to worsen. This report serves to highlight the importance of early disease identification and intervention in patients with hereditary hemochromatosis to prevent the development of neurological sequelae, as well as a need for further research into effective therapies in such patients.
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spelling pubmed-105447072023-10-03 Drug-Resistant Parkinson’s Disease in a Patient With Hereditary Hemochromatosis: A Case Report Banta, Conor W Zonna, Xavier Lott, Ronald Jaisawal, Pooja Elsisi, Amr Cureus Internal Medicine A 55-year-old male, with a strong family history of hereditary hemochromatosis, presented with progressively worsening right-sided tremor and Parkinsonian symptoms. He was diagnosed with hereditary hemochromatosis based on genetic testing and started undergoing regular phlebotomies to reduce his blood iron levels. Despite extensive trials of different pharmaceutical therapies, including levodopa-carbidopa, his Parkinsonian symptoms were not relieved and continued to worsen. This report serves to highlight the importance of early disease identification and intervention in patients with hereditary hemochromatosis to prevent the development of neurological sequelae, as well as a need for further research into effective therapies in such patients. Cureus 2023-09-01 /pmc/articles/PMC10544707/ /pubmed/37790065 http://dx.doi.org/10.7759/cureus.44530 Text en Copyright © 2023, Banta et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Banta, Conor W
Zonna, Xavier
Lott, Ronald
Jaisawal, Pooja
Elsisi, Amr
Drug-Resistant Parkinson’s Disease in a Patient With Hereditary Hemochromatosis: A Case Report
title Drug-Resistant Parkinson’s Disease in a Patient With Hereditary Hemochromatosis: A Case Report
title_full Drug-Resistant Parkinson’s Disease in a Patient With Hereditary Hemochromatosis: A Case Report
title_fullStr Drug-Resistant Parkinson’s Disease in a Patient With Hereditary Hemochromatosis: A Case Report
title_full_unstemmed Drug-Resistant Parkinson’s Disease in a Patient With Hereditary Hemochromatosis: A Case Report
title_short Drug-Resistant Parkinson’s Disease in a Patient With Hereditary Hemochromatosis: A Case Report
title_sort drug-resistant parkinson’s disease in a patient with hereditary hemochromatosis: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544707/
https://www.ncbi.nlm.nih.gov/pubmed/37790065
http://dx.doi.org/10.7759/cureus.44530
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