Cargando…
Fulminant Hepatic Failure With Minimal Alcohol Consumption in a 25-Year-Old Female With Hereditary Hemochromatosis: A Rare Case
Hereditary hemochromatosis (HH) is an inherited disorder in which organ damage and other clinical manifestations are commonly seen in patients with a homozygous mutation involving C282Y of the HFE gene, causing increased iron absorption in the intestine. The liver is the primary site of iron deposit...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544746/ https://www.ncbi.nlm.nih.gov/pubmed/37790043 http://dx.doi.org/10.7759/cureus.44544 |
_version_ | 1785114551936614400 |
---|---|
author | Alvi, Ali Tariq Santiago, Luis E Nadeem, Zahid Chaudhry, Ali |
author_facet | Alvi, Ali Tariq Santiago, Luis E Nadeem, Zahid Chaudhry, Ali |
author_sort | Alvi, Ali Tariq |
collection | PubMed |
description | Hereditary hemochromatosis (HH) is an inherited disorder in which organ damage and other clinical manifestations are commonly seen in patients with a homozygous mutation involving C282Y of the HFE gene, causing increased iron absorption in the intestine. The liver is the primary site of iron deposition, and excessive iron overload can eventually lead to hepatic cirrhosis. Patients who drink significant amounts of alcohol are more likely to develop cirrhosis, and in females, it is commonly seen after menopause. We describe a young female with hereditary hemochromatosis who developed fulminant hepatic failure with minimal alcohol consumption at age 25. |
format | Online Article Text |
id | pubmed-10544746 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-105447462023-10-03 Fulminant Hepatic Failure With Minimal Alcohol Consumption in a 25-Year-Old Female With Hereditary Hemochromatosis: A Rare Case Alvi, Ali Tariq Santiago, Luis E Nadeem, Zahid Chaudhry, Ali Cureus Internal Medicine Hereditary hemochromatosis (HH) is an inherited disorder in which organ damage and other clinical manifestations are commonly seen in patients with a homozygous mutation involving C282Y of the HFE gene, causing increased iron absorption in the intestine. The liver is the primary site of iron deposition, and excessive iron overload can eventually lead to hepatic cirrhosis. Patients who drink significant amounts of alcohol are more likely to develop cirrhosis, and in females, it is commonly seen after menopause. We describe a young female with hereditary hemochromatosis who developed fulminant hepatic failure with minimal alcohol consumption at age 25. Cureus 2023-09-01 /pmc/articles/PMC10544746/ /pubmed/37790043 http://dx.doi.org/10.7759/cureus.44544 Text en Copyright © 2023, Alvi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Alvi, Ali Tariq Santiago, Luis E Nadeem, Zahid Chaudhry, Ali Fulminant Hepatic Failure With Minimal Alcohol Consumption in a 25-Year-Old Female With Hereditary Hemochromatosis: A Rare Case |
title | Fulminant Hepatic Failure With Minimal Alcohol Consumption in a 25-Year-Old Female With Hereditary Hemochromatosis: A Rare Case |
title_full | Fulminant Hepatic Failure With Minimal Alcohol Consumption in a 25-Year-Old Female With Hereditary Hemochromatosis: A Rare Case |
title_fullStr | Fulminant Hepatic Failure With Minimal Alcohol Consumption in a 25-Year-Old Female With Hereditary Hemochromatosis: A Rare Case |
title_full_unstemmed | Fulminant Hepatic Failure With Minimal Alcohol Consumption in a 25-Year-Old Female With Hereditary Hemochromatosis: A Rare Case |
title_short | Fulminant Hepatic Failure With Minimal Alcohol Consumption in a 25-Year-Old Female With Hereditary Hemochromatosis: A Rare Case |
title_sort | fulminant hepatic failure with minimal alcohol consumption in a 25-year-old female with hereditary hemochromatosis: a rare case |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544746/ https://www.ncbi.nlm.nih.gov/pubmed/37790043 http://dx.doi.org/10.7759/cureus.44544 |
work_keys_str_mv | AT alvialitariq fulminanthepaticfailurewithminimalalcoholconsumptionina25yearoldfemalewithhereditaryhemochromatosisararecase AT santiagoluise fulminanthepaticfailurewithminimalalcoholconsumptionina25yearoldfemalewithhereditaryhemochromatosisararecase AT nadeemzahid fulminanthepaticfailurewithminimalalcoholconsumptionina25yearoldfemalewithhereditaryhemochromatosisararecase AT chaudhryali fulminanthepaticfailurewithminimalalcoholconsumptionina25yearoldfemalewithhereditaryhemochromatosisararecase |