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Exceptional reactivity of the bridgehead amine on bicyclo[1.1.1]pentane
Bicyclo[1.1.1]pentane (BCP) has received substantial interest in the field of synthetic chemistry recently for its potential use as a benzene isostere in medicinal chemistry. Whereas bicyclo[2.2.2]octane (BCO) has also been used as a bioisostere of benzene, the condensation of BCP-amine with nadic a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544781/ https://www.ncbi.nlm.nih.gov/pubmed/37786812 http://dx.doi.org/10.24820/ark.5550190.p012.003 |