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Digoxin protects against intervertebral disc degeneration via TNF/NF-κB and LRP4 signaling

BACKGROUND: Intervertebral disc degeneration (IVDD) is a leading cause of low back pain (LBP). The pathological process of IVDD is associated with inflammatory reactions and extracellular matrix (ECM) disorders. Digoxin is widely used for treating heart failure, and it has been reported to have anti...

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Detalles Bibliográficos
Autores principales:	Meng, Qunbo, Liu, Kaiwen, Liu, Zhenchuan, Liu, Jinbo, Tian, Ziyu, Qin, Shanshan, Wei, Jianlu, Cheng, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544936/ https://www.ncbi.nlm.nih.gov/pubmed/37790932 http://dx.doi.org/10.3389/fimmu.2023.1251517

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