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A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review

RATIONALE: Periodontitis is an inflammatory disease with multifactorial etiology. Vitamin D, a fat-soluble vitamin, has protective effects on inflammatory response in various systemic conditions. The clinical features of vitamin D deficiency include growth failure, hypotonia, pathologic fractures, r...

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Autores principales: Li, Chen, Zhang, Jinmei, Wang, Lufei, Yang, Jingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545046/
https://www.ncbi.nlm.nih.gov/pubmed/37773856
http://dx.doi.org/10.1097/MD.0000000000035321
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author Li, Chen
Zhang, Jinmei
Wang, Lufei
Yang, Jingmei
author_facet Li, Chen
Zhang, Jinmei
Wang, Lufei
Yang, Jingmei
author_sort Li, Chen
collection PubMed
description RATIONALE: Periodontitis is an inflammatory disease with multifactorial etiology. Vitamin D, a fat-soluble vitamin, has protective effects on inflammatory response in various systemic conditions. The clinical features of vitamin D deficiency include growth failure, hypotonia, pathologic fractures, rachitic rosary, tetany and so on. Here we present a case of 12-year-old girl affected by early-onset periodontitis accompanied with vitamin D deficiency. PATIENT CONCERNS: A 12-year-old girl with gingival redness, bleeding associated with tooth brushing, and mandibular anterior teeth movement, with difficulty in mastication for the past 2 months. There is no relevant family history or special systemic disease history. The serological microelement test showed vitamin D levels were significantly lower than normal range. Immunological test showed abnormal CD4(+)/CD8(+)(CD3(+)CD4(+)/CD3(+)CD8(+)) ratio as well. DIAGNOSES: Based on the clinical and serological findings, this patient was ultimately diagnosed with early-onset periodontitis accompanied with vitamin D deficiency. INTERVENTIONS: The main treatments for this patient were 3-fold: periodontal therapy, vitamin D supplement and oral hygiene instructions. OUTCOMES: Following 1-year therapy, periodontal conditions recovered and became stable. And serological vitamin D levels returned to normal range. LESSONS: The case of interest serves as an important reminder to clinicians, that the early-onset periodontitis may be associated with micronutrients abnormalities, and early-diagnosis and treatment could avoid the body heathy disorders.
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spelling pubmed-105450462023-10-03 A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review Li, Chen Zhang, Jinmei Wang, Lufei Yang, Jingmei Medicine (Baltimore) 5900 RATIONALE: Periodontitis is an inflammatory disease with multifactorial etiology. Vitamin D, a fat-soluble vitamin, has protective effects on inflammatory response in various systemic conditions. The clinical features of vitamin D deficiency include growth failure, hypotonia, pathologic fractures, rachitic rosary, tetany and so on. Here we present a case of 12-year-old girl affected by early-onset periodontitis accompanied with vitamin D deficiency. PATIENT CONCERNS: A 12-year-old girl with gingival redness, bleeding associated with tooth brushing, and mandibular anterior teeth movement, with difficulty in mastication for the past 2 months. There is no relevant family history or special systemic disease history. The serological microelement test showed vitamin D levels were significantly lower than normal range. Immunological test showed abnormal CD4(+)/CD8(+)(CD3(+)CD4(+)/CD3(+)CD8(+)) ratio as well. DIAGNOSES: Based on the clinical and serological findings, this patient was ultimately diagnosed with early-onset periodontitis accompanied with vitamin D deficiency. INTERVENTIONS: The main treatments for this patient were 3-fold: periodontal therapy, vitamin D supplement and oral hygiene instructions. OUTCOMES: Following 1-year therapy, periodontal conditions recovered and became stable. And serological vitamin D levels returned to normal range. LESSONS: The case of interest serves as an important reminder to clinicians, that the early-onset periodontitis may be associated with micronutrients abnormalities, and early-diagnosis and treatment could avoid the body heathy disorders. Lippincott Williams & Wilkins 2023-09-29 /pmc/articles/PMC10545046/ /pubmed/37773856 http://dx.doi.org/10.1097/MD.0000000000035321 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 5900
Li, Chen
Zhang, Jinmei
Wang, Lufei
Yang, Jingmei
A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review
title A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review
title_full A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review
title_fullStr A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review
title_full_unstemmed A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review
title_short A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review
title_sort case of early-onset periodontitis with vitamin d deficiency: a case report and literature review
topic 5900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545046/
https://www.ncbi.nlm.nih.gov/pubmed/37773856
http://dx.doi.org/10.1097/MD.0000000000035321
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