Disruption of the inositol phosphorylceramide synthase gene affects Trypanosoma cruzi differentiation and infection capacity

Sphingolipids (SLs) are essential components of all eukaryotic cellular membranes. In fungi, plants and many protozoa, the primary SL is inositol-phosphorylceramide (IPC). Trypanosoma cruzi is a protozoan parasite that causes Chagas disease (CD), a chronic illness for which no vaccines or effective...

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Detalles Bibliográficos
Autores principales: Dos Santos, Nailma S A, Estevez-Castro, Carlos F., Macedo, Juan P., Chame, Daniela F., Castro-Gomes, Thiago, Santos-Cardoso, Mariana, Burle-Caldas, Gabriela A., Covington, Courtney N., Steel, Patrick G., Smith, Terry K., Denny, Paul W., Teixeira, Santuza M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545103/
https://www.ncbi.nlm.nih.gov/pubmed/37729272
http://dx.doi.org/10.1371/journal.pntd.0011646

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