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BMP suppresses WNT to integrate patterning of orthogonal body axes in adult planarians

Adult regeneration restores patterning of orthogonal body axes after damage in a post-embryonic context. Planarians regenerate using distinct body-wide signals primarily regulating each axis dimension: anteroposterior Wnts, dorsoventral BMP, and mediolateral Wnt5 and Slit determinants. How regenerat...

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Detalles Bibliográficos
Autores principales: Clark, Eleanor G., Petersen, Christian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545109/
https://www.ncbi.nlm.nih.gov/pubmed/37729232
http://dx.doi.org/10.1371/journal.pgen.1010608