Cargando…

Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study

BACKGROUND: A variety of medications are available to manage painful diabetic peripheral neuropathy (DPN), but the proper treatment remains challenging. Accordingly, various neuromodulation modalities have been used. However, no prospective clinical trials have evaluated the use of scrambler therapy...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoo, Seung Hee, Kim, Won-joong, Chae, Ji Seon, Kang, Bo Kyung, Kang, Min Jeong, Beak, Min Hyouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545242/
https://www.ncbi.nlm.nih.gov/pubmed/37773810
http://dx.doi.org/10.1097/MD.0000000000035357
_version_ 1785114630115295232
author Yoo, Seung Hee
Kim, Won-joong
Chae, Ji Seon
Kang, Bo Kyung
Kang, Min Jeong
Beak, Min Hyouk
author_facet Yoo, Seung Hee
Kim, Won-joong
Chae, Ji Seon
Kang, Bo Kyung
Kang, Min Jeong
Beak, Min Hyouk
author_sort Yoo, Seung Hee
collection PubMed
description BACKGROUND: A variety of medications are available to manage painful diabetic peripheral neuropathy (DPN), but the proper treatment remains challenging. Accordingly, various neuromodulation modalities have been used. However, no prospective clinical trials have evaluated the use of scrambler therapy (ST) in painful DPN. This study aimed to explore the long-term effects of ST in managing painful DPN. METHODS: The patients received 10 consecutive STs of 45 minutes every 1 to 2 days. The primary outcome was pain score. We measured the visual analog scale (VAS) pain scores at baseline, during ST, immediately after ST, and at 1, 2, 3, and 6 months after ST. The secondary outcomes were Michigan Neuropathy Screening Instrument (MNSI), Semmes-Weinstein monofilament test, and Leeds Assessment of Neuropathic Symptoms and Signs pain scores, which were measured at baseline, immediately after ST, and at 1, 2, 3, and 6 months after ST. RESULTS: VAS scores showed significant improvement at the 8th, 9th, and 10th sessions during ST and 1 month after ST. The MNSI self-report component score was decreased 1 month after the ST. However, all other outcomes did not show significant differences compared to the baseline. CONCLUSION: ST may have short-term effects and limited long-term effects on painful DPN.
format Online
Article
Text
id pubmed-10545242
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-105452422023-10-03 Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study Yoo, Seung Hee Kim, Won-joong Chae, Ji Seon Kang, Bo Kyung Kang, Min Jeong Beak, Min Hyouk Medicine (Baltimore) 3300 BACKGROUND: A variety of medications are available to manage painful diabetic peripheral neuropathy (DPN), but the proper treatment remains challenging. Accordingly, various neuromodulation modalities have been used. However, no prospective clinical trials have evaluated the use of scrambler therapy (ST) in painful DPN. This study aimed to explore the long-term effects of ST in managing painful DPN. METHODS: The patients received 10 consecutive STs of 45 minutes every 1 to 2 days. The primary outcome was pain score. We measured the visual analog scale (VAS) pain scores at baseline, during ST, immediately after ST, and at 1, 2, 3, and 6 months after ST. The secondary outcomes were Michigan Neuropathy Screening Instrument (MNSI), Semmes-Weinstein monofilament test, and Leeds Assessment of Neuropathic Symptoms and Signs pain scores, which were measured at baseline, immediately after ST, and at 1, 2, 3, and 6 months after ST. RESULTS: VAS scores showed significant improvement at the 8th, 9th, and 10th sessions during ST and 1 month after ST. The MNSI self-report component score was decreased 1 month after the ST. However, all other outcomes did not show significant differences compared to the baseline. CONCLUSION: ST may have short-term effects and limited long-term effects on painful DPN. Lippincott Williams & Wilkins 2023-09-29 /pmc/articles/PMC10545242/ /pubmed/37773810 http://dx.doi.org/10.1097/MD.0000000000035357 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 3300
Yoo, Seung Hee
Kim, Won-joong
Chae, Ji Seon
Kang, Bo Kyung
Kang, Min Jeong
Beak, Min Hyouk
Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study
title Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study
title_full Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study
title_fullStr Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study
title_full_unstemmed Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study
title_short Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study
title_sort efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: a single-arm, prospective, pilot study
topic 3300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545242/
https://www.ncbi.nlm.nih.gov/pubmed/37773810
http://dx.doi.org/10.1097/MD.0000000000035357
work_keys_str_mv AT yooseunghee efficacyofscramblertherapyinpatientswithpainfuldiabeticperipheralneuropathyasinglearmprospectivepilotstudy
AT kimwonjoong efficacyofscramblertherapyinpatientswithpainfuldiabeticperipheralneuropathyasinglearmprospectivepilotstudy
AT chaejiseon efficacyofscramblertherapyinpatientswithpainfuldiabeticperipheralneuropathyasinglearmprospectivepilotstudy
AT kangbokyung efficacyofscramblertherapyinpatientswithpainfuldiabeticperipheralneuropathyasinglearmprospectivepilotstudy
AT kangminjeong efficacyofscramblertherapyinpatientswithpainfuldiabeticperipheralneuropathyasinglearmprospectivepilotstudy
AT beakminhyouk efficacyofscramblertherapyinpatientswithpainfuldiabeticperipheralneuropathyasinglearmprospectivepilotstudy