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Staphylococcal enterotoxin C as a novel strategy for treating lumbar spondylolysis in adolescents: Description of technique

Lumbar spondylolysis is one of the most common causes of low back pain and primarily affects children and adolescents. Traditional posterior lumbar fixation and interbody fusion surgery has always been the most effective method to treat spondylolysis. However, traditional surgical management has lim...

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Autores principales: Zhou, Hongdian, Deng, Kaiwen, Wang, Nan, Li, Hua, Xu, Zujian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545280/
https://www.ncbi.nlm.nih.gov/pubmed/37773848
http://dx.doi.org/10.1097/MD.0000000000035224
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author Zhou, Hongdian
Deng, Kaiwen
Wang, Nan
Li, Hua
Xu, Zujian
author_facet Zhou, Hongdian
Deng, Kaiwen
Wang, Nan
Li, Hua
Xu, Zujian
author_sort Zhou, Hongdian
collection PubMed
description Lumbar spondylolysis is one of the most common causes of low back pain and primarily affects children and adolescents. Traditional posterior lumbar fixation and interbody fusion surgery has always been the most effective method to treat spondylolysis. However, traditional surgical management has limitations of large trauma, complex operation, high cost, postoperative biomechanical deterioration, and resulting complications. In order to avoid the trauma and complications of surgical treatment, and reduce the cost of treatment. Based on the successful clinical experience of using staphylococcal enterotoxin C (SEC) to treat nonunion after a limb fracture, we identified a minimally invasive method to effectively treat lumbar spondylolysis. A novel minimally invasive therapeutic approach is presented herein of an SEC injection guided by C-arm fluoroscopy to treat lumbar spondylolysis. We describe a novel technique applied in a patient with lumbar spondylolysis, who showed significantly improved low back pain symptoms and a computed tomography scan, including osseous fusion of the bilateral isthmus at L4 after SEC therapy. This is the first reported case description of using an SEC injection to treat lumbar spondylolysis with a successful clinical outcome.
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spelling pubmed-105452802023-10-03 Staphylococcal enterotoxin C as a novel strategy for treating lumbar spondylolysis in adolescents: Description of technique Zhou, Hongdian Deng, Kaiwen Wang, Nan Li, Hua Xu, Zujian Medicine (Baltimore) 7100 Lumbar spondylolysis is one of the most common causes of low back pain and primarily affects children and adolescents. Traditional posterior lumbar fixation and interbody fusion surgery has always been the most effective method to treat spondylolysis. However, traditional surgical management has limitations of large trauma, complex operation, high cost, postoperative biomechanical deterioration, and resulting complications. In order to avoid the trauma and complications of surgical treatment, and reduce the cost of treatment. Based on the successful clinical experience of using staphylococcal enterotoxin C (SEC) to treat nonunion after a limb fracture, we identified a minimally invasive method to effectively treat lumbar spondylolysis. A novel minimally invasive therapeutic approach is presented herein of an SEC injection guided by C-arm fluoroscopy to treat lumbar spondylolysis. We describe a novel technique applied in a patient with lumbar spondylolysis, who showed significantly improved low back pain symptoms and a computed tomography scan, including osseous fusion of the bilateral isthmus at L4 after SEC therapy. This is the first reported case description of using an SEC injection to treat lumbar spondylolysis with a successful clinical outcome. Lippincott Williams & Wilkins 2023-09-29 /pmc/articles/PMC10545280/ /pubmed/37773848 http://dx.doi.org/10.1097/MD.0000000000035224 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 7100
Zhou, Hongdian
Deng, Kaiwen
Wang, Nan
Li, Hua
Xu, Zujian
Staphylococcal enterotoxin C as a novel strategy for treating lumbar spondylolysis in adolescents: Description of technique
title Staphylococcal enterotoxin C as a novel strategy for treating lumbar spondylolysis in adolescents: Description of technique
title_full Staphylococcal enterotoxin C as a novel strategy for treating lumbar spondylolysis in adolescents: Description of technique
title_fullStr Staphylococcal enterotoxin C as a novel strategy for treating lumbar spondylolysis in adolescents: Description of technique
title_full_unstemmed Staphylococcal enterotoxin C as a novel strategy for treating lumbar spondylolysis in adolescents: Description of technique
title_short Staphylococcal enterotoxin C as a novel strategy for treating lumbar spondylolysis in adolescents: Description of technique
title_sort staphylococcal enterotoxin c as a novel strategy for treating lumbar spondylolysis in adolescents: description of technique
topic 7100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545280/
https://www.ncbi.nlm.nih.gov/pubmed/37773848
http://dx.doi.org/10.1097/MD.0000000000035224
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