A novel protocol to derive cervical motor neurons from induced pluripotent stem cells for amyotrophic lateral sclerosis

Sporadic amyotrophic lateral sclerosis (sALS) is the majority of ALS, and the lack of appropriate disease models has hindered its research. Induced pluripotent stem cell (iPSC) technology now permits derivation of iPSCs from somatic cells of sALS patients to investigate disease phenotypes and mechan...

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Detalles Bibliográficos
Autores principales: Yang, Meimei, Liu, Min, Sánchez, Yajaira Feller, Avazzadeh, Sahar, Quinlan, Leo R., Liu, Gang, Lu, Yin, Yang, Guangming, O'Brien, Timothy, Henshall, David C., Hardiman, Orla, Shen, Sanbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545486/
https://www.ncbi.nlm.nih.gov/pubmed/37595581
http://dx.doi.org/10.1016/j.stemcr.2023.07.004

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