Cargando…
Spatiotemporal cell junction assembly in human iPSC-CM models of arrhythmogenic cardiomyopathy
Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac disorder that causes life-threatening arrhythmias and myocardial dysfunction. Pathogenic variants in Plakophilin-2 (PKP2), a desmosome component within specialized cardiac cell junctions, cause the majority of ACM cases. However, the molecu...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545490/ https://www.ncbi.nlm.nih.gov/pubmed/37595583 http://dx.doi.org/10.1016/j.stemcr.2023.07.005 |