Spatiotemporal cell junction assembly in human iPSC-CM models of arrhythmogenic cardiomyopathy

Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac disorder that causes life-threatening arrhythmias and myocardial dysfunction. Pathogenic variants in Plakophilin-2 (PKP2), a desmosome component within specialized cardiac cell junctions, cause the majority of ACM cases. However, the molecu...

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Detalles Bibliográficos
Autores principales: Kim, Sean L., Trembley, Michael A., Lee, Keel Yong, Choi, Suji, MacQueen, Luke A., Zimmerman, John F., de Wit, Lousanne H.C., Shani, Kevin, Henze, Douglas E., Drennan, Daniel J., Saifee, Shaila A., Loh, Li Jun, Liu, Xujie, Parker, Kevin Kit, Pu, William T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545490/
https://www.ncbi.nlm.nih.gov/pubmed/37595583
http://dx.doi.org/10.1016/j.stemcr.2023.07.005

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