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Metastatic Competency and Tumor Spheroid Formation Are Independent Cell States Governed by RB in Lung Adenocarcinoma

Inactivation of the retinoblastoma (RB) tumor suppressor in lung adenocarcinoma is associated with the rapid acquisition of metastatic ability and the loss of lung cell lineage commitment. We previously showed that restoration of RB in advanced lung adenocarcinomas in the mouse was correlated with a...

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Detalles Bibliográficos
Autores principales:	Freeburg, Nelson F., Peterson, Nia, Ruiz, Dain A., Gladstein, Amy C., Feldser, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545537/ https://www.ncbi.nlm.nih.gov/pubmed/37728504 http://dx.doi.org/10.1158/2767-9764.CRC-23-0172

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