A Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis–Based Antigen-Specific Immunotherapy in New-Onset Type 1 Diabetes

Immunomodulation combined with antigen therapy holds great promise to arrest autoimmune type 1 diabetes, but clinical translation is hampered by a lack of prognostic biomarkers. Low-dose anti-CD3 plus Lactococcus lactis bacteria secreting proinsulin and IL-10 reversed new-onset disease in nonobese d...

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Detalles Bibliográficos
Autores principales: Sassi, Gabriele, Licata, Giada, Ventriglia, Giuliana, Wouters, Amber, Lemaitre, Pierre, Seurinck, Ruth, Mori, Alessia, Grieco, Giuseppina Emanuela, Bissenova, Samal, Ellis, Darcy, Caluwaerts, Silvia, Rottiers, Pieter, Vandamme, Niels, Mathieu, Chantal, Dotta, Francesco, Gysemans, Conny, Sebastiani, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545562/
https://www.ncbi.nlm.nih.gov/pubmed/37494666
http://dx.doi.org/10.2337/db22-0852

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